The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low hemoglobin levels (67%)
- Low white blood cells (37%)
- Low sodium levels (46%)
- Higher liver enzyme levels (up to 33%)
- Low calcium levels (22%)
- High potassium levels (21%)
- High calcium levels (20%)
- Tiredness (19%)
- Muscle or bone pain (15%)
Less Common Side Effects
- Cough
- Shortness of breath
- Low appetite
- Injection site reactions
- Fever
Note: Side effects came from adults with NSCLC who took [[EDITOR|DRUG_DISPLAY_NAME]] alone. Side effects might be different for people with other cancers, for those also taking chemotherapy, or for children.
Tecentriq Hybreza serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Serious immune-related side effects: rash, blisters, skin peeling, trouble breathing, coughing, chest pain, severe diarrhea, severe stomach pain, mucus or blood in stool, not urinating as much
- Serious reaction during the injection: chills, shaking, rash, itching, flushing, dizziness, fever, throat tightness, trouble breathing, wheezing, back or neck pain, swelling of the face
When do Tecentriq Hybreza possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Injection reaction (redness, soreness)
Cough
Risk of rash
Risk of diarrhea
Risk of thyroid problems
Seek immediate medical care if you experience this side effect.
If a line continues to the right, you'll likely keep experiencing this side effect once it starts.
Source: FDA
The following Tecentriq Hybreza side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dry cough, shortness of breath or trouble breathing
- Eye pain, redness, irritation, or discharge with blurry or decreased vision
- Heart muscle inflammation—unusual weakness or fatigue, shortness of breath, chest pain, fast or irregular heartbeat, dizziness, swelling of the ankles, feet, or hands
- Hormone gland problems—headache, sensitivity to light, unusual weakness or fatigue, dizziness, fast or irregular heartbeat, increased sensitivity to cold or heat, excessive sweating, constipation, hair loss, increased thirst or amount of urine, tremors or shaking, irritability
- Injection reactions—chest pain, shortness of breath or trouble breathing, feeling faint or lightheaded
- Kidney injury (glomerulonephritis)—decrease in the amount of urine, red or dark brown urine, foamy or bubbly urine, swelling of the ankles, hands, or feet
- Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Rash, fever, and swollen lymph nodes
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Sudden or severe stomach pain, bloody diarrhea, fever, nausea, vomiting
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone, joint, or muscle pain
- Diarrhea
- Fatigue
- Loss of appetite
- Nausea
- Skin rash
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