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Imdelltra

Imdelltra Side Effects

Allison Baxley, PharmD, BCOPDaisy Chau, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Daisy Chau, PharmD
Last reviewed on December 18, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Lower white blood cells (84%)
  • Blood electrolyte changes (up to 68%)
  • Lower red blood cells (58%)
  • Cytokine release syndrome (55%)
  • Tiredness (51%)
  • Higher liver enzymes (up to 44%)
  • Fever (36%)
  • Changes in taste (36%)
  • Reduced appetite (34%)
  • Lower platelets (33%)
  • Constipation (30%)
  • Muscle pain (30%)
  • Higher creatinine level in blood (29%)
  • Nausea (22%)

Less Common Side Effects

  • Trouble breathing
  • Cough

Imdelltra serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Cytokine release syndrome (CRS): Fever, trouble breathing, chills, dizziness, fast heartbeat, headache, feeling anxious
  • Nervous system problems: headache, numbness, dizziness, confusion, sleepiness, trouble speaking or writing, shaking, muscle weakness, pain, seizures
  • Serious infection: fever, body aches, chills, feeling very tired or weak, very fast heartbeat, cough, chest pain, shortness of breath, rash, sore throat
  • Liver problems: pain in the right upper stomach yellowing of the skin or eyes, tiredness, loss of appetite, dark urine
  • Severe allergic reactions: trouble breathing, wheezing, coughing, lightheaded, dizziness, rash
When do Imdelltra possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Cytokine release syndrome
Nervous system problems
Seek immediate medical care if you experience this side effect.

Source: DailyMed

The following Imdelltra side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness or fatigue
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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