The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Low white blood cells (up to 90%)
- Low fibrinogen in blood (84%)
- Low red blood cells (72%)
- Cytokine release syndrome (70%)
- Changes in blood electrolytes (up to 69%)
- Low platelets (56%)
- Blood electrolyte changes (up to 49%)
- Muscle pain (21%)
- Tiredness (20%)
- Rash (20%)
Less Common Side Effects
- Swelling
- Fever
- Constipation
- Diarrhea
- Tumor flare
- Headache
- Nausea
- Stomach pain
- Vomiting
- Tremor
Columvi serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Cytokine release syndrome (CRS): fever, chills or shaking, fast or irregular heartbeat, dizziness or light-headedness, trouble breathing, shortness of breath
- Nervous system problems: headache, confusion, difficulty paying attention or understanding things, trouble speaking, sleepiness, memory problems, dizziness, numbness or tingling of the hands or feet, shaking
- Serious infection: fever, chills, weakness, cough, shortness of breath, sore throat
- Tumor flare: tender or swollen lymph nodes, pain or swelling at the site of the tumor, chest pain, cough, trouble breathing
When do Columvi possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Cytokine release syndrome
Tumor flare
Seek immediate medical care if you experience this side effect.
Source: DailyMed
The following Columvi side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dizziness, loss of balance or coordination, confusion or trouble speaking
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Swelling and pain of the tumor site or lymph nodes
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
- Bone pain
- Constipation
- Diarrhea
- Fatigue
- Muscle pain
- Skin rash
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