The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
DLBCL and high-grade B-cell lymphoma:
- Low white blood cells (up to 87%)
- Low red blood cells (62%)
- Cytokine release syndrome (51%)
- Electrolyte changes in blood (up to 56%)
- Higher liver enzymes in blood (up to 48%)
- Low platelets (48%)
- Tiredness (29%)
- Muscle pain (28%)
- Injection site reactions (27%)
- Fever (24%)
- Stomach pain (23%)
- Diarrhea (20%)
- Nausea (20%)
Follicular lymphoma:
- Injection site reactions (58%)
- Cytokine release syndrome (49%)
- COVID-19 (40%)
- Tiredness (37%)
- Upper respiratory tract infection (29%)
- Muscle pain (28%)
- Rash (28%)
- Fever (26%)
- Diarrhea (26%)
- Nausea (20%)
- Cough (20%)
Less Common Side Effects
DLBCL and high-grade B-cell lymphoma:
- Swelling
- Rash
- Headache
- Vomiting
- Lower appetite
Follicular lymphoma:
- Swelling
- Pneumonia
- Urinary tract infection
- Herpes infection
- Joint pain
- Nausea
- Stomach pain
- Constipation
- Mouth sores
- Dizziness
- Trouble sleeping
Epkinly serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Cytokine release syndrome (CRS): fever, chills, low blood pressure, fast heartbeat, trouble breathing, headache
- Nervous system problems: headache, numbness, dizziness, confusion, sleepiness
- Serious infection: fever, body aches, chills, feeling very tired or weak, very fast heartbeat, cough, chest pain, shortness of breath, rash, sore throat
Source: DailyMed
The following Epkinly side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dizziness, loss of balance or coordination, confusion or trouble speaking
- Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
- Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
- Pain, tingling, or numbness in the hands or feet, muscle weakness, change in vision, confusion or trouble speaking, loss of balance or coordination, trouble walking, seizures
- Unusual bruising or bleeding
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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