Typical dosage for Epkinly
The recommended dose follows a step-up schedule. Each dose is given as an injection under the skin, starting with a low dose and increasing to the highest dose. The typical maintenance dose is 48 mg. Each treatment cycle lasts 28 days.
DLBCL or high-grade B-cell lymphoma:
- Cycle 1
- Day 1: 0.16 mg, Day 8: 0.8 mg, Day 15: 48 mg, Day 22: 48 mg
- Cycles 2 and 3
- Day 1: 48 mg, Day 8: 48 mg, Day 15: 48 mg, Day 22: 48 mg
- Cycles 4 to 9
- Day 1: 48 mg, Day 15: 48 mg
- Cycles 10 and beyond:
- Day 1: 48 mg
Follicular lymphoma:
- Cycle 1
- Day 1: 0.16 mg, Day 8: 0.8 mg, Day 15: 3 mg, Day 22: 48 mg
- Cycles 2 and 3
- Day 1: 48 mg, Day 8: 48 mg, Day 15: 48 mg, Day 22: 48 mg
- Cycles 4 to 9
- Day 1: 48 mg, Day 15: 48 mg
- Cycles 10 and beyond
- Day 1: 48 mg
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