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Elrexfio

Elrexfio Dosage

Allison Baxley, PharmD, BCOPConnie Zheng, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Connie Zheng, PharmD
Last reviewed on August 6, 2024

Typical dosage for Elrexfio

Elrexfio is injected under the skin by a trained healthcare professional on your oncology team, typically in a hospital or clinic setting.

  • Starting dose (“step-up” dosing): During your first week of treatment, your oncologist will raise your dose over the course of a week.
    • Day 1 dose: 12 mg injected once.
    • Day 4 dose: 32 mg injected once.
    • Day 8 dose: 76 mg injected once.
  • Maintenance dose: Starting a week after the last dose, your oncologist will inject 76 mg under the skin once a week.
    • If the medication works well for you for at least 6 months, your oncologist might lower your dose to 76 mg once every two weeks.

Your oncologist will also prescribe several medications before the first three doses to help prevent a serious side effect called cytokine release syndrome. These include dexamethasone and diphenhydramine (Benadryl).

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