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Lunsumio

Lunsumio Side Effects

Allison Baxley, PharmD, BCOPDaisy Chau, PharmD
Reviewed by Allison Baxley, PharmD, BCOP, Daisy Chau, PharmD
Last reviewed on January 8, 2025

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Low white blood cells (100%)
  • Blood electrolyte changes (up to 78%)
  • Low red blood cells (68%)
  • Low platelets (46%)
  • Cytokine release syndrome (44%)
  • Higher blood sugar (42%)
  • Tiredness (42%)
  • Liver enzyme changes (up to 39%)
  • Rash (39%)
  • Headache (32%)
  • Fever (29%)
  • Muscle pain (28%)
  • Cough (22%)
  • Itching (21%)
  • Numbness (20%)

Less Common Side Effects

  • Chills
  • Cough
  • Swelling
  • Diarrhea
  • Nausea
  • Stomach pain
  • Dry skin
  • Dizziness
  • Joint pain
  • Shortness of breath
  • Trouble sleeping

Lunsumio serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Cytokine release syndrome (CRS): fever, chills, low blood pressure, fast heartbeat, trouble breathing, headache
  • Nervous system problems: headache, numbness, dizziness, confusion, sleepiness
  • Serious infection: fever, body aches, chills, feeling very tired or weak, very fast heartbeat, cough, chest pain, shortness of breath, rash, sore throat
  • Hemophagocytic lymphohistiocytosis (HLH): fever, easy bruising, liver problems
  • Tumor flare: chest pain, trouble breathing, cough, swollen lymph nodes, pain or swelling at the tumor site

Source: DailyMed

The following Lunsumio side effects have also been reported

Side effects that you should report to your care team as soon as possible:

  • Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Fever, chills, unusual weakness or fatigue, loss of appetite, nausea, headache, dizziness, feeling faint or lightheaded, shortness of breath, fast or irregular heartbeat, which may be signs of cytokine release syndrome
  • Infection—fever, chills, cough, sore throat, wounds that don't heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
  • Low red blood cell level—unusual weakness or fatigue, dizziness, headache, trouble breathing
  • Pain, tingling, or numbness in the hands or feet, muscle weakness, headache, change in vision, confusion or trouble speaking, dizziness, loss of balance or coordination, trouble walking, tremors or shaking, seizures
  • Swelling and pain of the tumor site or lymph nodes
  • Unusual bruising or bleeding

Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):

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