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Dermatology

How Patients Can Save on 6 Types of Derm Medications Insurance May Not Cover

Stacia Woodcock, PharmDMaria Robinson, MD, MBA
Written by Stacia Woodcock, PharmD | Reviewed by Maria Robinson, MD, MBA
Published on October 7, 2026

Key takeaways:

  • Many dermatology medications aren’t covered by insurance, especially when they’re prescribed for cosmetic concerns.

  • Comparison shopping is beneficial for treatments that have limited coverage or high out-of-pocket costs.

  • GoodRx discounts, manufacturer savings programs, and lower-cost generics can also help lower out-of-pocket costs.

It’s no surprise to dermatology prescribers that many medications are unlikely to be covered by prescription insurance plans since they’re often considered cosmetic.

If a patient’s insurance doesn’t cover a dermatology medication, or it requires a high-cost copay, there are ways to help lower the cost. Below, we’ll cover common self-pay dermatology medications and ways to save on these prescriptions.

1. Topical retinoids

A few topical retinoids are FDA approved for improving skin appearance and acne, but others are prescribed off-label. Insurance plans are less likely to cover off-label prescriptions and those with cosmetic, rather than medical, applications. So it’s common for patients to self-pay for topical retinoids.

This chart shows common prescription retinoids that may not be covered by insurance, their average cash price, and how patients can save on their cost. Note that in some cases, brand-name Retin-A may be more affordable than the generic version.

Tretinoin (Retin-A)

Medication name: Generic (brand)

Average cash price

GoodRx low price

Retin-A 0.01% gel, 45 g

$89.04

$51.25

Retin-A 0.025% gel, 45 g

$89.04

$51.25

Retin-A 0.025% cream, 45 g

$89.04

$51.25

Retin-A 0.05% cream, 45 g

$89.04

$51.25

Retin-A 0.1% cream, 45 g

$89.04

$51.25

Tretinoin 0.01% gel, 45 g

$195.52

$68.15

Tretinoin 0.025% gel, 45 g

$94.94

$34.67

Tretinoin 0.025% cream, 45 g

$94.94

$34.67

Tretinoin 0.05% cream, 45 g

$94.94

$34.67

Tretinoin 0.1% cream, 45 g

$94.94

$34.67

Tretinoin micro (Retin-A micro)

As little as $25 each for brand-name Retin-A Micro 0.06% and 0.08% gel pump with a manufacturer copay card.

Medication name: Generic (brand)

Average cash price

GoodRx low price

Tretinoin micro 0.04% gel, 45 g

$539.75

$154.38

Tretinoin micro, 0.1% gel, 45 g

$527.59

$158.12

Tretinoin emollient (Renova)

Medication name: Generic (brand)

Average cash price

GoodRx low price

Renova 0.02% cream, 40 g

$322.95

$279.65

Refissa (branded generic) 0.05% cream, 40 g

$322.95

$72.10

Tazarotene (Tazorac)

Other ways to save: As little as $125 per tube for brand-name Tazorac with a manufacturer savings card.

Medication name: Generic (brand)

Average cash price

GoodRx low price

Tazarotene 0.05% cream, 30 g

$451.60

$120.43

Tazarotene 0.05% gel, 30 g

$422.44

$100.42

Tazarotene 0.1% cream, 30 g

$190.10

$40.00

Tazarotene 0.1% gel, 30 g

$472.28

$110.76

Adapalene (Differin)

Medication name: Generic (brand)

Average cash price

GoodRx low price

Adapalene 0.3% gel, 45 g

$272.79

$30.00

Adapalene 0.1% cream, 45 g

$180.95

$30.00

Adapalene 0.1% gel, 45 g

$90.93

$10.75

OTC Differin 0.1% gel

$38.27

$27.51

Keep in mind: Patients must have a prescription to use a GoodRx discount on over-the-counter (OTC) Differin.

2. Hair-loss medications

Medications that treat hair loss are often considered cosmetic, and thus are often self-pay.

The chart below shows common prescription medications for hair loss that may not be covered by insurance, their average cash price, and how to save on their cost.

Finasteride (Propecia)

Other ways to save: Pay as little as $16 per month for finasteride with GoodRx for Hair Loss.

Medication name: Generic (brand)

Average cash price

GoodRx low price

Finasteride (Propecia) 1 mg 30 tablets

$45.80

$10.50

Dutasteride (Avodart)

Medication name: Generic (brand)

Average cash price

GoodRx low price

*Dutasteride (Avodart) 0.5 mg, 30 capsules

$168.31

$12.90

*Off-label use

Minoxidil (Rogaine, Loniten)

Medication name: Generic (brand)

Average cash price

GoodRx low price

Minoxidil 5% foam 60 g

$22.96

$28.31

Minoxidil 5% liquid 60 mL

$22.96 

$28.31 

Minoxidil 2% liquid 60 mL

$22.96

$28.31 

*Minoxidil tablets 2.5 mg, 30 tablets

$13.34

$10.50

*Off-label use

Keep in mind: Patients must have a prescription to use GoodRx discount on OTC minoxidil products.

3. Medications for eyelash growth and blepharoptosis

Two unique cosmetic medications are Latisse (bimatoprost) for eyelash hypotrichosis and Upneeq (oxymetazoline) for acquired blepharoptosis. These are often self-pay dermatology medications, since their use is cosmetic. But there are still ways to reduce the cost of these treatments, as shown in this chart.

Bimatoprost

Medication name

Average cash price

GoodRx low price

Bimatoprost 0.03% 5 mL

$185.48

$59.88

Upneeq

Other ways to save: As low as $139.50 for 30 vials with a subscription service through the manufacturer.

Medication name

Average cash price

GoodRx low price

Upneeq 0.1% 30 single-use vials

$267.05

N/A

4. Rosacea treatments

Many prescription treatments for rosacea are covered by insurance. This is especially true for older medications with lower-cost generics, such as metronidazole gel (Metrogel) and azelaic acid (Finacea).

But newer rosacea medications are less likely to have insurance coverage or may have a higher copay than expected. Thankfully, many of these products have savings programs or other ways to reduce your cost. See the chart below for average cash prices of common self-pay rosacea medications and other ways to save.

Rhofade (oxymetazoline)

Other ways to save: Pay as little as $0 per month (with commercial insurance coverage) or $50 per month (if coverage is denied) with a coupon card from the manufacturer.

Medication name

Average cash price

GoodRx low price

Rhofade (oxymetazoline) 1% cream, 30 g

$871.54

$45.00(exclusive GoodRx savings)

Zilxi (minocycline)

Other ways to save: Pay as little as $25 per month (with insurance coverage) with a copay card from the manufacturer.

Medication name

Average cash price

GoodRx low price

Zilxi (minocycline) 1.5% foam, 30 g

$615.59

$371.61

Soolantra (ivermectin)

Other ways to save: Pay as little as $20 for brand-name Soolantra (with insurance coverage) using a copay card from the manufacturer.

Medication name

Average cash price

GoodRx low price

Ivermectin 1% cream, 45 g

$314.18

$99.43

Brimonidine (Mirvaso)

Medication name

Average cash price

GoodRx low price

Brimonidine (Mirvaso) 0.33% gel pump, 30 g

$453.06

$311.98

5. Medications for hyperpigmentation and melasma

Several topical prescription medications can help with skin discoloration. But, again, these treatments are often considered cosmetic.

This chart shows common prescription medications for skin discoloration that may not be covered by insurance, their average cash price, and how patients can save.

Hydroquinone

Medication name

Average cash price

GoodRx low price

Hydroquinone 4% cream 28.35 g

$66.63

$26.00

Tri-Luma (fluocinolone / hydroquinone / tretinoin)

Other ways to save: As low as $20 with insurance and $90 without insurance per tube with a manufacturer discount card.

Medication name

Average cash price

GoodRx low price

Tri-Luma (fluocinolone / hydroquinone / tretinoin) 0.05% cream 30 g

$296.51

$227.92

Finacea (azelaic acid)

Other ways to save: As low as $30 per can of brand-name Finacea foam with a manufacturer copay card.

Medication name

Average cash price

GoodRx low price

Azeleic acid 15% gel 50 g

$223.98

$36.03

6. Topical nail antifungals

Topical liquid medications can help treat toenail fungus, but they aren’t as effective as oral options. Here are some options (often not covered by insurance) with average cash price and other ways to save.

Ciclopirox (generic Penlac)

Medication name

Average cash price

GoodRx low price

Ciclopirox (generic Penlac) 8% solution, 6.6 mL

$75.68

$21.53

Ciclodan (ciclopirox)

Medication name

Average cash price

GoodRx low price

Ciclodan (ciclopirox) 8% solution, 6.6 mL

$24.42

$24.42

Jublia (efinaconazole)

Other ways to save: A little as $0 per month with a manufacturer copay card (with insurance coverage) or patient assistance program (without insurance coverage).

Medication name

Average cash price

GoodRx low price

Jublia (efinaconazole) 10% solution, 4 mL

$984.11

$829.24

Tavaborole (Kerydin)

Medication name

Average cash price

GoodRx low price

Tavaborole (Kerydin) 5% solution, 10 mL

$1198.16

$47.28

Other ways to save

For those still having trouble accessing dermatology medications at an affordable price, here are some other things to try:

  • Consider GoodRx Companion: Over 250 medications are available for free and hundreds more for under $10 per month with a GoodRx Companion subscription. This program also includes benefits to help users cut other self-pay costs, such as lower prices for telehealth and discounts on dental care.

  • Compare pharmacy prices: Out-of-pocket prices can differ between pharmacies, even within the same area. GoodRx can help patients compare prices and transfer their prescription to a more affordable location if needed.

The bottom line

Many dermatology medications aren’t covered by insurance, especially when they’re prescribed for cosmetic concerns. Treatments for conditions such as rosacea and toenail fungus may also have limited coverage or high out-of-pocket costs. For difficult-to-access medications, consider GoodRx discounts, manufacturer savings cards, and lower-cost generic options.

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Why trust our experts?

Stacia Woodcock, PharmD, is a pharmacy editor for GoodRx. She earned her Doctor of Pharmacy degree from the University of Kentucky and is licensed in New York and Massachusetts.
Mandy Armitage, MD, has combined clinical medicine with her passion for education and content development for many years. She is co-executive director at Nonclinical Physicians Network and has served as medical director for the health technology companies HealthLoop (now Get Well) and Doximity.
Maria Robinson, MD, MBA, is a board-certified dermatologist and dermatopathologist who has practiced dermatology and dermatopathology for over 10 years across private practice, academic, and telehealth settings. She is a fellow of the American Academy of Dermatology and the American Society of Dermatopathology.

References

Bausch Health. (n.d.). Eligible Bausch Health medications.

Finacea. (n.d.). Save with LEO Pharma Connect.

Galderma CareConnect. (n.d.). The patient savings program for adults.

Journey Medical. (2022). Start saving on Zilxy today.

Mayne Pharma. (2025). Eligibility criteria.

National Rosacea Society. (2026). New review highlights disparities in insurance coverage for topical rosacea therapies.

Ortho Dermatologics. (n.d.). Rx access program.

Tazorac. (2026). East, affordable access to Almirall’s Tazorac (tazarotene) cream 0.05%, 0.1%. Almirall. 

Upneeq. (n.d.). Upneeq. RVL Pharmaceuticals.

GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. Learn more about how we ensure our content is accurate, thorough, and unbiased by reading our editorial guidelines.

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