Enzyme replacement therapies are used to treat lysosomal storage disease, pancreatic insufficiency, and PKU. They work by increasing levels of certain enzymes in the body to delay symptoms.

Why are
Enzyme Replacement Therapies
prescribed?

How is this chart calculated?

How we make this chart

This chart is created by aggregating the total number of claims for the drugs in this class divided by the # of drugs with a specific indication. It is meant to be representative but may not accurately reflect the actual # of prescriptions written to treat a specific condition.

Prices for Popular Enzyme Replacement Therapies

Popularity Brand Name (Generic Name) GoodRx Fair Price Price Trend
Creon
474
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PANCRELIPASE helps to improve digestion of food by replacing digestive enzymes. This medicine is used to treat health conditions that cause your body to produce less of these enzymes.
Zenpep
461
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PANCRELIPASE helps to improve digestion of food by replacing digestive enzymes. This medicine is used to treat health conditions that cause your body to produce less of these enzymes.
Pancreaze
236
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PANCRELIPASE helps to improve digestion of food by replacing digestive enzymes. This medicine is used to treat health conditions that cause your body to produce less of these enzymes.
Kuvan
8,053
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SAPROPTERIN works to lower phenylalanine levels in the blood. It is used with a special diet to treat phenylketonuria. This medicine is not a cure.
Pertzye
376
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PANCRELIPASE helps to improve digestion of food by replacing digestive enzymes. This medicine is used to treat health conditions that cause your body to produce less of these enzymes.
Viokace
600
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PANCRELIPASE helps to improve digestion of food by replacing digestive enzymes. This medicine is used to treat health conditions that cause your body to produce less of these enzymes.
Cerdelga
24,455
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ELIGLUSTAT is used for the long-term treatment of adults with Gaucher disease type I. Eliglustat is not used in certain people with Gaucher disease type 1. Your doctor will perform a test to make sure this medicine is right for you.
Buphenyl
(sodium phenylbutyrate)
519
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SODIUM PHENYLBUTYRATE (sow dee um fen il bue ti rate) is used to manage the amount of ammonia in the blood of patients with urea cycle disorders. This medicine is not a cure.
Aldurazyme
866
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LARONIDASE is a drug that is used to replace an enzyme that is missing in patients with some forms of mucopolysaccharidosis I (MPS I). It is used to treat some of the symptoms of the disease. This medicine is not a cure.
Lumizyme
770
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ALGLUCOSIDASE ALFA is a drug that is used to replace an enzyme that is missing in patients with Pompe disease. It is not a cure.
Strensiq
N/A
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Orfadin
2,497
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NITISINONE slows the breakdown of tyrosine. It is used to treat a rare disease called hereditary tyrosinemia type I.
Kanuma
N/A N/A See Prices
Elelyso
789
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Taliglucerase alfa is a man-made form of an enzyme that is missing in patients with Gaucher's disease. It is used to treat the symptoms of Gaucher's disease. It is not a cure.
Xuriden
44,963
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URIDINE TRIACETATE increases the amount of uridine in your body. Xuriden is used to replace uridine in patients with hereditary orotic aciduria. It is not a cure. Vistogard is used to treat an overdose or reduce the harmful effects of fluorouracil or capecitabine.
Naglazyme
1,850
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GALSULFASE is an enzyme replacement. It is used to treat the symptoms of mucopolysaccharidosis VI (also known as MPS VI or Maroteaux-Lamy syndrome). This medicine is not a cure.
Ravicti
3,826
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GLYCEROL PHENYLBUTYRATE (gli ser ol fen il bue ti rate) is used to manage the amount of ammonia in the blood of patients with urea cycle disorders. This medicine is not a cure.
Myozyme
982
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Vimizim
1,189
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ELOSULFASE ALFA is an enzyme replacement. It is used to treat the symptoms of Mucopolysaccharidosis type IVA (MPS IVA; Morquio A syndrome). This medicine is not a cure.
Vpriv
1,422
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Velaglucerase alfa is a man-made form of an enzyme that is missing in patients with Gaucher's disease. It is used to treat the symptoms of Gaucher's disease. It is not a cure.
Cerezyme
867
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IMIGLUCERASE is a man-made form of an enzyme that is missing in patients with Gaucher's disease. It is used to treat the symptoms of Gaucher's disease. It is not a cure.
Elaprase
3,029
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IDURSULFASE is used to replace an enzyme that is missing in patients with Hunter syndrome. It is not a cure.
Fabrazyme
5,695
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AGALSIDASE BETA is used to replace an enzyme that is missing in patients with Fabry disease. It is not a cure.
Vistogard
3,799
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URIDINE TRIACETATE increases the amount of uridine in your body. Xuriden is used to replace uridine in patients with hereditary orotic aciduria. It is not a cure. Vistogard is used to treat an overdose or reduce the harmful effects of fluorouracil or capecitabine.
Ultresa
139
See Prices

Note: Popularity is based on total prescriptions for the brand and generic versions of each drug, regardless of the condition being treated. Some drugs are prescribed for multiple conditions.

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