Xuriden

Uridine triacetate

Used for Anemia

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Xuriden (uridine triacetate) is a medication taken by mouth to treat a rare genetic disorder called hereditary orotic aciduria. It's available as packets of granules that must be mixed with liquid or soft food.

Reviewed by:

Kristianne Hannemann, PharmD

Allison Gourley, PharmD

Last reviewed on April 10, 2022

Basics Pharmacist tips FAQs Dosage Cost Images Prices Medicare

What is Xuriden (uridine triacetate)?

Are you looking for information on Vistogard (uridine triacetate) instead?

Drug facts

Common BrandsXuriden

Drug ClassPyrimidine analog

Controlled Substance ClassificationNot a controlled medication

Generic StatusNo lower-cost generic available

AvailabilityPrescription only

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Avg retail price

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$47635.69

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Pharmacist tips for Xuriden (uridine triacetate)

Xuriden (uridine triacetate) comes as packets containing 2 grams of granules each. Your provider will prescribe the exact dose you need based on your body weight. You'll need to measure your dose by weighing the granules with a scale or by using a measuring spoon. If you have any questions about measuring the correct dose of Xuriden (uridine triacetate), ask your provider or pharmacist.
Since the dose of Xuriden (uridine triacetate) is based on body weight, tell your provider if you or your child experiences any weight changes so they can adjust the dose.
Once you open a packet and measure your dose of Xuriden (uridine triacetate), throw away any unused granules left in the opened packet since they might not work as well if you save them for later.
Make sure to keep up on all of your lab work so your provider can monitor how well Xuriden (uridine triacetate) is working for you and adjust your dose if needed.
Before taking Xuriden (uridine triacetate), read the instructions to make sure you're comfortable.

Mixing Xuriden (uridine triacetate) with soft food

To prepare your dose of Xuriden (uridine triacetate) with food, place 3 to 4 ounces of applesauce, pudding, or yogurt in a clean container. Add the measured Xuriden (uridine triacetate) granules and mix them in.
Swallow the mixture right away and don't chew the granules or this can damage the medication. Don't save any of the mixture for later use, since it might not work as well for you.
After you've swallowed your dose of Xuriden (uridine triacetate), drink at least 4 ounces of water to wash the granules down.

Mixing Xuriden (uridine triacetate) with milk or infant formula

Xuriden (uridine triacetate) can be prepared with milk or infant formula if you're using 2 grams or less of medication. To do so, pour 5 mL of milk or formula into a 30 mL cup. Then, draw up the 5 mL of liquid into an oral syringe. Turn the syringe so its tip is pointing up and pull the plunger to the 10 mL line to add air into it. Place the cap on and remove the plunger while the tip is pointing down.
Add the measured granules to the syringe and reinsert the plunger. Gently swirl the syringe to mix the granules and liquid, then remove the cap and push the plunger until it reaches the 5 mL mark while the tip is pointing up to remove the air.
Place the syringe in your child's mouth between the cheek and gum at the back of their mouth and gently push the plunger all the way in.
Refill the syringe with another 5 mL of milk or formula and swirl to rinse any remaining granules and repeat giving it to your child in their mouth.
You can give more milk or formula after giving your child Xuriden (uridine triacetate) if you'd like.

Common questions about Xuriden (uridine triacetate)

Xuriden (uridine triacetate) is used to treat a very rare genetic condition called hereditary orotic aciduria. If you have this condition, your body can't make uridine, an important compound needed for life. As a result, you can experience many complications, such as blood problems and developmental problems. Xuriden (uridine triacetate) is a pyrimidine analog, it treats hereditary orotic aciduria by replacing the uridine that's missing in your body.

Dosing of Xuriden (uridine triacetate) is based on your body weight. The typical starting dose is 60 mg/kg by mouth once daily. Your provider might raise your dose to 120 mg/kg once daily (not to exceed 8 grams per day), depending on your response.

Xuriden (uridine triacetate) comes as packets of granules. You can measure out your dose either with a scale or with a measuring spoon. Then, mix your medication with soft food (e.g., applesauce, pudding, or yogurt), water, milk, or infant formula, and take by mouth. Never chew or crush the granules since this can damage the medication and you might not get your full dose.

There isn't enough information available to know if Xuriden (uridine triacetate) is safe to take during pregnancy. In animal studies, high doses of Xuriden (uridine triacetate) didn't cause harm to pregnant mothers and their unborn babies. If you're pregnant or thinking of becoming pregnant, speak to your provider about the risks and benefits of this medication for you and your unborn baby.

No side effects have been reported with Xuriden (uridine triacetate) during clinical studies. But these studies only involved a very small number of people with hereditary orotic aciduria, so the results might not apply to everyone who receive treatment. If you suspect any side effects while taking it, make sure to let your provider know.

No, Xuriden (uridine triacetate) isn't the same as Vistogard (uridine triacetate). While both Xuriden and Vistogard contain uridine triacetate granules as the active medication, only Xuriden is approved to treat hereditary orotic aciduria. Vistogard is used to treat serious side effects from certain chemotherapy medications. Double check your medication when you pick it up at your pharmacy to make sure the right one is dispensed. Speak with your provider if you've any questions about wither Xuriden or Vistogard is right for you.