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Compare Creon vs. Zenpep

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Creon (pancrelipase)
    Zenpep (pancrelipase)
  • Creon (pancrelipase)
    Zenpep (pancrelipase)

  • Summary of Creon vs. Zenpep

    Summary for Enzyme replacement therapy
    Prescription only

    Creon (pancrelipase) is a prescription medication that contains pancreatic enzymes to help you digest food if your body doesn't make enough of them. It's used in both children and adults to treat exocrine pancreatic insufficiency (EPI). The medication comes as a pill that you take by mouth with every meal and snack to help break down food. The dose depends on your weight, age, and how much fat you eat, and it might be adjusted over time. Common side effects include cough, stomach pain, and vomiting.

    Summary for Enzyme replacement therapy
    Prescription only

    Zenpep (pancrelipase) is a prescription medication used for children and adults with exocrine pancreatic insufficiency (EPI), a condition where the pancreas doesn’t make enough enzymes to digest food. It contains pancreatic enzymes that help break down fats, carbohydrates, and proteins so your body can absorb nutrients. You take the capsule by mouth with every meal and snack, and your dose is based on your weight, age, and diet. Common side effects include cough, headache, and feeling full quickly. Right now, there isn’t a generic version of Zenpep (pancrelipase) available.

  • Indications of Creon vs. Zenpep

    Indications for
    •Exocrine pancreatic insufficiency (EPI)
    Indications for
    •Exocrine pancreatic insufficiency

  • Pros and Cons of Creon vs. Zenpep

    Pros and Const for Enzyme replacement therapy
    Pros
    •Capsules can be opened up and mixed with certain soft foods
    •Safe for children and infants
    •Comes in multiple strengths
    •No known interactions with other medications
    Cons
    •Must be taken with every meal and snack
    •Might not be safe to take for people with pork allergy
    •Can cause stomach pain and vomiting
    •Dose adjustment can take a while
    Pros and Const for Enzyme replacement therapy
    Pros
    •Capsules can be opened up and mixed with certain soft foods
    •Safe for children and infants
    •Comes in multiple strengths
    •No known interactions with other medications
    Cons
    •Must be taken with every meal and snack
    •Might not be safe to take for people with pork allergy
    •Can cause stomach pain and vomiting
    •Dose adjustment can take a while

  • Common Side Effects of Creon vs. Zenpep

    Common Side Effects for

    Adults and children 7 years and older with cystic fibrosis:

    •Vomiting (6%)
    •Dizziness (4%)
    •Cough (4%)

    Children ages 4 months to 6 years old with cystic fibrosis:

    •Vomiting (6%)
    •Irritability (6%)
    •Reduced appetite (6%)

    Adults with chronic pancreatitis or pancreas removal surgery:

    •High blood sugar (8%)
    •Low blood sugar (4%)
    •Stomach pain (4%)
    •Abnormal stool (4%)
    •Passing gas (4%)
    •Frequent bowel movements (4%)
    •Common cold symptoms (4%)
    Common Side Effects for

    Adults and children 7 years and older with cystic fibrosis:

    •Headache (15%)
    •Bruising (6%)
    •Cough (6%)
    •Feeling full soon after eating (6%)

    Children 1 to 6 years old with cystic fibrosis:

    •Stomach pain
    •Fatty stools

  • Warnings of Creon vs. Zenpep

    Common Side Effects for
    •Scarring in the colon (fibrosing colonopathy)
    •Mouth irritation
    •High uric acid levels
    •Possible risk of infection
    •Severe allergic reactions
    Common Side Effects for
    •Scarring in the colon (fibrosing colonopathy)
    •Mouth irritation
    •High uric acid levels
    •Possible risk of infection
    •Severe allergic reaction

  • Prices with our coupons for Creon vs. Zenpep

    Learn more about Creon
    Learn more about Zenpep

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