Cyclomydril
Cyclomydril (cyclopentolate / phenylephrine) is a combination eyedrop containing cyclopentolate and phenylephrine. The two medications work well together, but the combination product costs more than generic cyclopentolate and phenylephrine eyedrops combined.
What is Cyclomydril (cyclopentolate / phenylephrine)?
What is Cyclomydril (cyclopentolate / phenylephrine) used for?
- Pupil dilation
How Cyclomydril (cyclopentolate / phenylephrine) works
Cyclomydril (cyclopentolate / phenylephrine) is a combination of two medications. Cyclopentolate is an anticholinergic medication, and phenylephrine is an adrenergic medication. The two medications work together to dilate (widen) the pupil and paralyze certain muscles in your eye in preparation for an eye exam.
Drug facts
| Common Brands | Cyclomydril |
|---|---|
| Drug Class | Anticholinergic / Adrenergic receptor agonist |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | No lower-cost generic available |
| Availability | Prescription only |
Side effects of Cyclomydril (cyclopentolate / phenylephrine)
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- High eye pressure
- Eye burning and irritation
- Sensitivity to light
- Blurry vision
- Inflamed cornea
Less Common Side Effects
Medication absorbed through the tear duct can cause erratic (unpredictable) behavior in children, such as:
- Loss of balance and coordination
- Slurred speech
- Restlessness
- Hyperactivity
- Not knowing place and time
- Cannot recognize people
Cyclomydril (cyclopentolate / phenylephrine) serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Seizures (if absorbed through the tear duct in children)
The following Cyclomydril (cyclopentolate / phenylephrine) side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Symptoms of too much medicine being absorbed into the body
Clumsiness or unsteadiness
confusion or unusual behavior
dryness of skin
fast or irregular heartbeat
flushing or redness of face
seeing, hearing, or feeling things that are not there
skin rash
slurred speech
swollen stomach in infants
thirst or unusual dryness of mouth
unusual drowsiness, tiredness, or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Blurred vision
brief burning or stinging of the eyes
eye irritation not present before use of this medicine
increased sensitivity of eyes to light
swelling of the eyelids
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of Cyclomydril (cyclopentolate / phenylephrine)
Pros
- Convenient; two medications in one eye drop
- The two medications work together to provide better results.
- Effects are temporary and wear off within a day.
Cons
- Can make your eyes sensitive to light
- Interacts with medications used to lower eye pressure
- Not a good option for people with certain types of glaucoma
Pharmacist tips for Cyclomydril (cyclopentolate / phenylephrine)
- Always wash your hands before using Cyclomydril (cyclopentolate / phenylephrine) drops to prevent spreading bacteria to your eyes. Don't let the dropper touch your eye or any other surface. This can also cause an infection.
- After putting drops in your eye, use your finger to apply pressure on the tear duct (the inner corner of your eye) for 2 to 3 minutes. This will help keep the medication in your eye and stop it from being absorbed by your body.
- If you're helping a child with these eye drops, make sure you don't get any medication in their mouth or on their hands. If swallowed, children can be very sensitive to the side effects of the medication.
- Your dilated eyes are more sensitive to the light. Wearing sunglasses when you're outside can be helpful.
- Avoid driving after using Cyclomydril (cyclopentolate / phenylephrine), because your vision might be blurry.
Risks and warnings for Cyclomydril (cyclopentolate / phenylephrine)
Cyclomydril (cyclopentolate / phenylephrine) can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
For use in the eyes only
Cyclomydril (cyclopentolate / phenylephrine) should only be used in the eyes. If the medication is injected or swallowed, it can cause many unpleasant side effects, especially in infants and children.
Use in infants and children
Cyclomydril (cyclopentolate / phenylephrine) may cause mood and behavioral changes in infants and young children. Children who swallow or absorb too much medication can have erratic (unpredictable) behavior and life-threatening side effects, such as seizures, hallucinations, impaired balance and coordination, confusion, and restlessness. Watch children closely for at least 30 minutes after applying Cyclomydril (cyclopentolate / phenylephrine). If you think your child has taken too much Cyclomydril (cyclopentolate / phenylephrine), call their provider or the poison control center at 1-800-222-1222 right away. Don't feed infants for 4 hours after using Cyclomydril (cyclopentolate / phenylephrine) because of possible feeding problems, like upset stomach and diarrhea.
Temporary rise in eye pressure
- Risk factors: History of untreated narrow-angle glaucoma | Taking medications to lower eye pressure | History of Down syndrome
Cyclomydril (cyclopentolate / phenylephrine) may temporarily raise your eye pressure after administration. This is especially true for people with untreated glaucoma or people with conditions like Down syndrome that may make them more likely to have eye problems. Let your healthcare provider know your entire vision and eye health history before using Cyclomydril (cyclopentolate / phenylephrine).
Cyclomydril (cyclopentolate / phenylephrine) dosage
Interactions between Cyclomydril (cyclopentolate / phenylephrine) and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.
- Aceclofenac
- Acemetacin
- Amtolmetin Guacil
- Aspirin
- Bromfenac
- Bufexamac
- Celecoxib
- Choline Salicylate
- Clonixin
- Clorgyline
- Dexibuprofen
- Dexketoprofen
- Diclofenac
- Diflunisal
- Dihydroergotamine
- Dipyrone
- Droxicam
- Etodolac
- Etofenamate
- Etoricoxib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Floctafenine
- Flufenamic Acid
- Flurbiprofen
- Ibuprofen
- Indomethacin
- Iproniazid
- Isocarboxazid
- Ketoprofen
- Linezolid
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Morniflumate
- Nabumetone
- Naproxen
- Nepafenac
- Nialamide
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Oxaprozin
- Oxyphenbutazone
- Parecoxib
- Pentoxifylline
- Phenelzine
- Phenylbutazone
- Piketoprofen
- Piroxicam
- Probenecid
- Procarbazine
- Proglumetacin
- Propyphenazone
- Proquazone
- Rasagiline
- Rofecoxib
- Salicylic Acid
- Salsalate
- Selegiline
- Sodium Salicylate
- Sulfasalazine
- Sulindac
- Tenoxicam
- Tiaprofenic Acid
- Tolfenamic Acid
- Tolmetin
- Tranylcypromine
- Valdecoxib
Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abciximab
- Acenocoumarol
- Amifampridine
- Amiloride
- Amineptine
- Amitriptyline
- Amitriptylinoxide
- Amoxapine
- Anagrelide
- Apixaban
- Ardeparin
- Argatroban
- Bemiparin
- Bendroflumethiazide
- Benzthiazide
- Betamethasone
- Betrixaban
- Bivalirudin
- Budesonide
- Bumetanide
- Bupropion
- Cangrelor
- Certoparin
- Chlorothiazide
- Chlorthalidone
- Cilostazol
- Citalopram
- Clomipramine
- Clopamide
- Clopidogrel
- Clozapine
- Cortisone
- Cyclopenthiazide
- Cyclosporine
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Deflazacort
- Desipramine
- Desirudin
- Desmopressin
- Desvenlafaxine
- Dexamethasone
- Diazoxide
- Dibenzepin
- Digoxin
- Dipyridamole
- Donepezil
- Dothiepin
- Doxepin
- Duloxetine
- Edoxaban
- Enoxaparin
- Eplerenone
- Epoprostenol
- Eptifibatide
- Erdafitinib
- Ergonovine
- Escitalopram
- Ethacrynic Acid
- Feverfew
- Fluocortolone
- Fluoxetine
- Fluvoxamine
- Fondaparinux
- Furazolidone
- Furosemide
- Ginkgo
- Glucagon
- Glycopyrrolate
- Glycopyrronium Tosylate
- Gossypol
- Heparin
- Hydrochlorothiazide
- Hydrocortisone
- Hydroflumethiazide
- Iloprost
- Imipramine
- Indapamide
- Inotersen
- Iobenguane I 123
- Iobenguane I 131
- Lepirudin
- Levomilnacipran
- Lithium
- Lofepramine
- Meadowsweet
- Melitracen
- Methacholine
- Methotrexate
- Methyclothiazide
- Methylergonovine
- Methylprednisolone
- Metolazone
- Midodrine
- Milnacipran
- Nadroparin
- Nefazodone
- Nortriptyline
- Opipramol
- Paramethasone
- Pargyline
- Parnaparin
- Paroxetine
- Pemetrexed
- Pentosan Polysulfate Sodium
- Phenindione
- Phenprocoumon
- Polythiazide
- Prasugrel
- Prednisolone
- Prednisone
- Protein C
- Protriptyline
- Quetiapine
- Reboxetine
- Revefenacin
- Reviparin
- Rivaroxaban
- Scopolamine
- Secretin Human
- Sertraline
- Sibutramine
- Spironolactone
- Tacrolimus
- Tenofovir Disoproxil Fumarate
- Tianeptine
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tiotropium
- Tirofiban
- Torsemide
- Trazodone
- Treprostinil
- Triamterene
- Trichlormethiazide
- Trimipramine
- Venlafaxine
- Vilazodone
- Vorapaxar
- Vortioxetine
- Warfarin
- Xipamide
How much does Cyclomydril (cyclopentolate / phenylephrine) cost?
$45.09
Cyclomydril (cyclopentolate / phenylephrine) contraindications
Contraindications are specific health conditions or situations in which a person should not take a medication due to safety concerns. If you have any of the following conditions or if any of the following apply to you, let your healthcare provider know because Cyclomydril (cyclopentolate / phenylephrine) will not be safe for you to take.
- Untreated narrow-angle glaucoma
What are alternatives to Cyclomydril (cyclopentolate / phenylephrine)?
Cyclomydril (cyclopentolate / phenylephrine) images
