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Zyrtec-D vs. Rhinocort Allergy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Zyrtec-D (cetirizine/pseudoephedrine) and Rhinocort Allergy (budesonide) are both used to treat allergy symptoms, but they work in different ways and have distinct characteristics. Zyrtec-D combines an antihistamine (cetirizine) and a decongestant (pseudoephedrine) to relieve allergies and congestion, and it is taken orally. It is available over the counter but requires a photo ID for purchase due to pseudoephedrine regulations. Rhinocort Allergy, on the other hand, is a corticosteroid nasal spray that reduces inflammation directly in the nose and is also available over the counter. Zyrtec-D can cause trouble sleeping and may raise blood pressure, while Rhinocort Allergy can lead to nosebleeds, fungal infections, or delayed growth in children with long-term use. Rhinocort Allergy is used once daily, whereas Zyrtec-D is typically taken every 12 hours. Additionally, both are available in a lower-cost generic form, making them affordable options for some.

Zyrtec-D

(cetirizine / pseudoephedrine)

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Budesonide nasal spray

(Rhinocort Allergy)

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Summary for Zyrtec-D

Over-the-counter

Zyrtec-D is a combination medication containing cetirizine (an antihistamine) and pseudoephedrine (a decongestant). It's taken by people ages 12 years and older to relieve allergy symptoms, like runny nose and nasal congestion. This medication comes as an extended-release tablet that's taken by mouth every 12 hours. Zyrtec-D is available as a brand-name and generic medication. Side effects can include trouble sleeping and dry mouth.

Indications for Zyrtec-D

Short-term relief of allergy symptoms in adults and children ages 12 years and older:

  • Itchy nose or throat
  • Sneezing
  • Itchy or watery eyes
  • Runny or stuffy nose
  • Sinus congestion or pressure

Pros and Cons for Zyrtec-D

Pros

  • Starts working within an hour
  • Easier to take a combination pill instead of two separate pills to treat congestion and other allergy symptoms
  • Available over the counter (behind the counter)

Cons

  • Might need to take twice daily
  • Tablets can't be crushed or chewed and there isn't a liquid version available
  • Not the safest choice if you have certain conditions, like heart problems and trouble urinating

Common Side Effects for Zyrtec-D

Warnings for Zyrtec-D

  • Fast heart rate and high blood pressure
  • Worsening of certain medical conditions
  • Accidentally taking too much medication

Summary for Rhinocort Allergy

Over-the-counter

Budesonide nasal spray (Rhinocort Allergy) is an over-the-counter (OTC) allergy medication for adults and children age 6 years and older. It's a corticosteroid that relieves nasal allergy symptoms, such as runny or stuffy nose, itchy nose, and sneezing. Budesonide nasal spray (Rhinocort Allergy) is sprayed into each nostril once per day. Side effects can include nose bleeds and irritation in the nose. This medication is available as a generic.

Indications for Rhinocort Allergy

Pros and Cons for Rhinocort Allergy

Pros

  • First-choice medication for treating nasal allergy symptoms
  • Only used once per day
  • Available over the counter
  • Can be used for children as young as 6 years old

Cons

  • Might cause nose bleeds
  • Might take up to 2 weeks to feel the full benefits from the medication
  • Not meant for relieving nasal symptoms related to the common cold

Common Side Effects for Rhinocort Allergy

  • Bloody nose (8%)
  • Sore throat (4%)

Warnings for Rhinocort Allergy

  • Nose bleeds, discomfort, and injury
  • Risk of infection
  • Altered stress hormone levels
  • Delayed growth in children
  • Allergic reactions
  • Eye and vision problems

Prices with our coupons for Zyrtec-D vs. Rhinocort Allergy

Price Card Drug Icon
Cetirizine/Pseudoephedrine24 tablets / 12 hour
$21.40-
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Price Card Drug Icon
Rhinocort Allergy1 nasal spray / 60 sprays of 32mcg
--
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