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Dexedrine vs. Adderall

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Dextroamphetamine (Dexedrine Spansule, ProCentra, Zenzedi) and Adderall (dextroamphetamine/amphetamine salts) are both stimulant medications used to treat attention deficit-hyperactivity disorder (ADHD) and narcolepsy. They share similar side effects, such as trouble sleeping and loss of appetite. However, they differ in their composition and formulation. Dextroamphetamine is a single-ingredient medication available in immediate-release tablets, extended-release capsules, and a liquid solution, while Adderall is a combination of dextroamphetamine and amphetamine salts available as an immediate-release tablet. Both medications are available as lower-cost generics, but Adderall does not come in a liquid form. Both medications can be used in children as young as 3 years old. Both medications have a risk of misuse and dependency, and they can interact with other medications, especially those affecting serotonin levels. It's important to follow your healthcare provider's instructions when taking these medications to avoid withdrawal symptoms and other risks.

Dextroamphetamine

 

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Adderall

 

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Summary for Dexedrine

Prescription only

Dextroamphetamine is used for the treatment of attention deficit-hyperactivity disorder (ADHD). It can also be used to treat uncontrollable daytime sleepiness (narcolepsy). Some side effects of the medication include difficulty sleeping, restlessness, and loss of appetite (that might lead to possible weight loss).

Indications for Dexedrine

  • Attention deficit-hyperactivity disorder (ADHD)
  • Narcolepsy (extreme daytime sleepiness)

Pros and Cons for Dexedrine

Pros

  • Available as a lower-cost generic medication
  • Available in immediate-release tablets and extended-release capsules
  • Available as a liquid solution if you have difficulty swallowing pills
  • Tablets and solution are okay to use in children as young as 3 years old

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Can cause trouble sleeping if taken late in the day
  • Not the best option if you have heart problems

Common Side Effects for Dexedrine

  • Fast heartbeat
  • Loss of appetite
  • Stomach upset
  • Dry mouth
  • Dizziness
  • Headache
  • Tremors
  • Trouble sleeping

Warnings for Dexedrine

  • Misuse and dependence
  • Serious heart-related problems
  • Aggressive behavior and psychosis
  • Slowed growth in children
  • Seizures
  • Blood circulation problems (such as Raynaud's phenomenon)
  • Serotonin syndrome
  • Interactions with other medications

Summary for Adderall

Prescription only

Adderall is a stimulant medication that's used to treat attention deficit-hyperactivity disorder (ADHD) and narcolepsy in adults and children. It contains the instant-release (IR) forms of dextroamphetamine and amphetamine salts. Adderall is available as a brand-name and lower-cost generic tablet that's taken by mouth. Your psychiatrist will adjust the dosage for you based on how well the medication works for you. Common side effects include trouble sleeping and loss of appetite.

Indications for Adderall

Pros and Cons for Adderall

Pros

Cons

  • Has a risk of misuse and dependency
  • A controlled medication, so there are special requirements for getting the prescription filled
  • Dose needs to be raised and lowered slowly to avoid side effects and withdrawal symptoms
  • Not available as a liquid or patch form (unlike methylphenidate (Ritalin))

Common Side Effects for Adderall

  • Upset stomach
  • Lower appetite
  • Weight loss
  • Nervousness
  • Changes in mood
  • Trouble sleeping

Warnings for Adderall

  • Misuse and addiction
  • Dependence and withdrawal
  • Serious heart problems
  • Aggressive behavior and psychosis
  • Slowed growth in children
  • Seizures
  • Blood circulation problems (such as Raynaud's phenomenon)
  • Serotonin syndrome
  • Drug interactions

Prices with our coupons for Dexedrine vs. Adderall

Price Card Drug Icon
Dextroamphetamine60 tablets / 10mg
$44.41$151.69
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Amphetamine Salt Combo30 tablets / 20mg
$16.99$50.44
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