Key takeaways
Vraylar (cariprazine) and lithium are both used to treat bipolar disorder, but they have some key differences. Vraylar is an atypical antipsychotic that also treats schizophrenia and can be an add-on for major depressive disorder (MDD). It is taken once a day and is only available as a brand-name medication. Common side effects include uncontrolled muscle movements, headache, and restlessness. Lithium, on the other hand, is a mood stabilizer used specifically for bipolar disorder and manic episodes. It is available in both generic and brand-name forms (Lithobid) and is typically taken 2 to 3 times a day. Lithium requires regular blood tests to monitor levels and prevent toxicity, with common side effects like shakiness, thirst, and nausea. While Vraylar has a lower risk of weight gain compared to other antipsychotics, lithium does not commonly cause weight gain but can lead to serious side effects if not monitored properly.
