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Vigamox vs. Cortisporin

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Moxifloxacin (Vigamox) and neomycin/polymyxin/hydrocortisone (Cortisporin) are both prescription medications, but they treat different types of infections and are used in different parts of the body. Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic used as eye drops to treat bacterial conjunctivitis (pink eye). It works by blocking proteins that bacteria need to grow and survive. On the other hand, neomycin/polymyxin/hydrocortisone (Cortisporin) is a combination of two antibiotics and a corticosteroid used as ear drops to treat outer ear infections. The antibiotics kill bacteria, while the corticosteroid reduces swelling and itching. Moxifloxacin (Vigamox) is typically used three times a day for seven days, while neomycin/polymyxin/hydrocortisone is used three or four times a day, with the dosage varying for adults and children. Both medications are available in generic forms, making them more affordable. However, neomycin/polymyxin/hydrocortisone carries a risk of hearing loss if used for more than 10 days, while moxifloxacin (Vigamox) can cause eye discomfort and should not be used with contact lenses.

Moxifloxacin

(Vigamox)

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Cortisporin Otic

 

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Summary for Vigamox

Prescription only

Moxifloxacin (Vigamox) is a fluoroquinolone antibiotic that treats bacterial conjunctivitis (pink eye) in people of all ages. It's an eye drop that's placed in the affected eye(s) 3 times per day for 7 days. Side effects aren't common but can include dry eye, eye pain, eye redness, and itchy eyes. This medication is available as a brand-name and generic version.

Indications for Vigamox

Pros and Cons for Vigamox

Pros

  • Can typically start to improve symptoms in a few days
  • Generally used less often during the day than alternatives
  • Safe to use in children and infants
  • Available as a lower-cost generic

Cons

  • Need to use 3 times a day
  • Can cause eye discomfort
  • Might be difficult for some people to use properly

Common Side Effects for Vigamox

  • Eye inflammation or redness (up to 6%)
  • Blurry vision (up to 6%)
  • Dry eye (up to 6%)
  • Eye irritation, pain, or itching (up to 6%)
  • Watery eye (up to 6%)

Warnings for Vigamox

  • For use in the eye only
  • Risk of developing new infection
  • Don't wear contact lenses
  • Severe allergic reaction

Summary for Cortisporin

Prescription only

Cortisporin Otic is an ear drop that contains three medications: two antibiotics (neomycin, polymyxin) and a corticosteroid (hydrocortisone). It's a good option for treating outer ear infections in adults and children. The typical dose is to place 3 to 4 drops into the affected ear three to four times a day for up to 10 days. Some people have reported burning and stinging as side effects. Brand name Cortisporin Otic has been discontinued; this medication is only available as a generic.

Indications for Cortisporin

Pros and Cons for Cortisporin

Pros

  • Contains three medications that work together to kill the bacteria and treat ear discomfort
  • Available as a lower-cost generic medication
  • Can be used with a cotton wick

Cons

  • One of the antibiotic ingredients (neomycin) can damage hearing.
  • Might cause burning when applied
  • Can't be used if you have a torn ear drum or chickenpox

Common Side Effects for Cortisporin

  • Burning
  • Stinging

Warnings for Cortisporin

  • Hearing loss
  • Allergic reaction
  • New infection

Prices with our coupons for Vigamox vs. Cortisporin

Price Card Drug Icon
Moxifloxacin1 eye dropper / 3ml of 0.5%
$16.48$213.86
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Neomycin/Polymyxin B/Hydrocortisone1 eye dropper / 7.5ml
$51.71$189.11
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