Key takeaways
Cefpodoxime (Vantin) and cefuroxime axetil (Ceftin) are both cephalosporin antibiotics used to treat bacterial infections, but they have some differences. Cefpodoxime, available as a generic, is a third-generation cephalosporin, while cefuroxime axetil, also available as a generic, is a second-generation cephalosporin. Cefpodoxime is typically taken twice a day and is used for a variety of infections, including strep throat, pneumonia, and UTIs. On the other hand, cefuroxime axetil is also taken twice a day but can treat additional infections like Lyme disease and is available in both tablet and injection forms. Both medications can cause side effects like diarrhea and nausea, but cefuroxime axetil has fewer common side effects reported. Additionally, cefuroxime axetil tablets should not be crushed due to their bitter taste, whereas cefpodoxime tablets should not be crushed because it can affect how the medication works. Both antibiotics should be taken exactly as prescribed to avoid the risk of developing drug-resistant bacteria.
