Key takeaways
Calcium carbonate (Tums, Pepto Kids) and bismuth subsalicylate (Pepto-Bismol, Kaopectate) are both over-the-counter medications, but they have several differences. Calcium carbonate is an antacid used to relieve heartburn, indigestion, and upset stomach by neutralizing stomach acid. It can also be used as a calcium supplement. On the other hand, bismuth subsalicylate is an antidiarrheal that treats diarrhea and various stomach symptoms like nausea, gas, and indigestion by slowing down gut movement and helping reabsorb fluids. Calcium carbonate is safe for children as young as 2 years old, while bismuth subsalicylate should not be given to children under 12 due to the risk of Reye's syndrome. Additionally, calcium carbonate can cause constipation, whereas bismuth subsalicylate may lead to dark-colored tongue and stools. Both medications come in various formulations, including chewable tablets and oral solutions. But they should not be taken for more than a few days without consulting a healthcare professional.
