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Tresiba vs. Toujeo

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Tresiba (insulin degludec) and Toujeo (insulin glargine) are both long-acting insulins used to manage diabetes, but they have some key differences. Tresiba is only available as a brand-name medication, while Toujeo also comes in brand-name forms but is a more concentrated version of insulin glargine. Tresiba can be used in children as young as 1 year old, whereas Toujeo is approved for children starting at 6 years old. Tresiba works up to 42 hours once injected, while Toujeo can work up to 36 hours. Both medications are injected under the skin once daily, but Tresiba offers more flexibility as it can be taken at any time of the day. Additionally, Tresiba pens can be stored at room temperature for up to 56 days, similar to Toujeo pens. Both insulins can cause low blood sugar and weight gain, but they should not be mixed with other insulins.

Insulin degludec

(Tresiba)

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Toujeo

(insulin glargine)

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Summary for Tresiba

Prescription only

Insulin degludec (Tresiba) is an ultra-long-acting insulin. It's used to manage blood sugar levels in adults and children with Type 1 diabetes or Type 2 diabetes. It's injected under the skin once per day. Insulin degludec (Tresiba) comes as a vial and FlexTouch pen. Side effects include common cold symptoms and headache. Tresiba is available as a brand-name medication and an unbranded biologic.

Indications for Tresiba

Pros and Cons for Tresiba

Pros

  • Injected once daily
  • Each dose can help control blood sugar levels for about 42 hours
  • Can be stored at room temperature for up to 2 months

Cons

Common Side Effects for Tresiba

  • Low blood sugar levels (up to 99%)
  • Common cold (up to 24%)
  • Upper respiratory tract infection (up to 12%)
  • Headache (up to 12%)
  • Diarrhea (up to 6%)
  • Sinus infection (up to 5%)
  • Stomach viral infection (up to 5%)

Warnings for Tresiba

  • Risk of infections with pen sharing
  • Risk of high and low blood sugar levels
  • Dangerously low blood sugar levels (hypoglycemia)
  • Low blood potassium levels
  • Swelling and heart failure when used with certain diabetes medications
  • Allergic reactions

Summary for Toujeo

Prescription only

Toujeo SoloStar and Toujeo Max SoloStar are a pair of brand names for insulin glargine. It's a long-acting insulin that's used for diabetes in adults and children. This medication is a more concentrated version of insulin glargine containing 300 units/mL. Toujeo (insulin glargine) comes as prefilled pens. You inject the medication under the skin once daily. Side effects include common cold symptoms and low blood sugar.

Indications for Toujeo

Pros and Cons for Toujeo

Pros

  • Long-lasting insulin that provides consistent, all-day blood sugar control
  • Given once a day
  • Available as a prefilled pen
  • Good choice for people who need high doses of long-acting insulin
  • Can use in children as young as 6 years old

Cons

  • Must inject under the skin
  • Might be hard for some people to administer correctly
  • Has a risk of causing low blood sugar (hypoglycemia)
  • Might cause weight gain
  • Can't mix with other insulins

Common Side Effects for Toujeo

Warnings for Toujeo

  • Risk of infections with pen sharing
  • Risk of changes to blood sugar levels with changes to your insulin regimen
  • Low blood sugar (hypoglycemia)
  • Low potassium levels
  • Swelling and heart failure when used with certain diabetes medications
  • Allergic reactions

Prices with our coupons for Tresiba vs. Toujeo

Price Card Drug Icon
Insulin Degludec1 vial / 10ml of 100 units/ml
$122.89$142.36
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Price Card Drug Icon
Toujeo1 carton / 3 prefilled 1.5ml pens of 300 units/ml
$367.08$521.32
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