Key takeaways
Quetiapine (Seroquel) and alprazolam (Xanax) are both medications that can be used to treat mood-related conditions, but they belong to different medication classes and have different uses. Quetiapine is an atypical antipsychotic used for schizophrenia, bipolar disorder, and as an add-on for depression, while alprazolam is a benzodiazepine approved for generalized anxiety disorder (GAD) and panic disorder. Quetiapine is available in immediate-release and extended-release tablets and is typically taken once to three times a day, depending on the condition. Alprazolam is taken by mouth, usually three times a day, and is available in immediate-release tablets, orally disintegrating tablets, and oral solution. Both medications are available as a lower-cost generic, but alprazolam is a controlled substance due to its potential for misuse and dependence. Common side effects of quetiapine include sleepiness and weight gain, while alprazolam can cause drowsiness and memory problems. Both medications can interact with other drugs, but opioids and alcohol increase the risk for severe side effects when taken with alprazolam.
