Key takeaways
Rytary (carbidopa/levodopa) and Stalevo (carbidopa/levodopa/entacapone) are both used to treat symptoms of Parkinson's disease, but they have some key differences. Rytary is an extended-release capsule that combines carbidopa and levodopa, and it helps by increasing dopamine levels in the brain. It is taken three times a day and is not available in a generic form, which can make it more expensive. On the other hand, Stalevo combines carbidopa, levodopa, and entacapone into a single pill, which helps extend the effect of the medication and reduce "off" periods when symptoms return. Stalevo is available in a lower-cost generic version and comes in six different strengths. However, it can cause long-term diarrhea and changes in the color of your bodily fluids. Both medications can make you very sleepy and cause you to fall asleep suddenly, so you should be cautious when driving or doing activities that require concentration.
