Skip to main content

Compare
Phenylephrine vs. Sudafed PE Pressure and Pain

Head-to-head comparisons of medication uses, side effects, warnings, and more.

phenylephrine eye drops

 

Get free coupons

Sudafed PE Pressure and Pain

(acetaminophen / phenylephrine)

Get free coupons

Summary for Phenylephrine

Prescription only

Phenylephrine eye drops are used to dilate (widen) pupils for eye exams or certain eye procedures. Side effects include temporary burning or stinging in the eye, blurry vision, and possibly raise your blood pressure. Let your provider know if your pregnant or breastfeeding because you might need to use a different medication.

Indications for Phenylephrine

  • Dilate (widen) pupils

Pros and Cons for Phenylephrine

Pros

  • Can be used in adults and children
  • Starts working quickly (within 15 minutes)
  • Available as a lower-cost generic medication

Cons

  • Can cause eye pain and stinging
  • Dilating effects can last for up to 7 hours (or longer)
  • The 10% strength can raise blood pressure in people with certain heart or thyroid problems

Common Side Effects for Phenylephrine

  • Temporary stinging or burning in your eye
  • Temporary blurry vision
  • Sensitivity to light

Warnings for Phenylephrine

  • For use in the eyes only
  • Heart problems
  • High blood pressure
  • Rebound pupil constriction

Summary for Sudafed PE Pressure and Pain

Over-the-counter

Sudafed PE Pressure and Pain is an over-the-counter, brand-name product containing two active ingredients: acetaminophen (an analgesic that relieves pain) and phenylephrine (a decongestant that clears the sinuses). This combination medication is also available as lower-cost generics and under other brand names, such as Tylenol Sinus Plus Headache. In general, it's used to relieve symptoms from allergies and the common cold, such as pain and nasal and sinus congestion. This medication can also lower fevers. The caplets are taken by mouth every 4 hours as needed. Side effects aren't common but can include headache and dizziness.

Indications for Sudafed PE Pressure and Pain

  • Short-term relief of allergy and common cold symptoms, such as sinus congestion and pressure, nasal congestion (stuffy nose), headache, and minor aches and pains
  • Short-term relief of fever

Pros and Cons for Sudafed PE Pressure and Pain

Pros

  • Can treat a wide variety of allergy and common cold symptoms
  • More convenient to take two medications in one pill
  • Available over the counter
  • Available as lower-cost generics

Cons

  • Might need to take every 4 hours to relieve symptoms
  • More difficult to customize the dose since it's a combination of two medications
  • Risk for liver damage if you take too much

Common Side Effects for Sudafed PE Pressure and Pain

Warnings for Sudafed PE Pressure and Pain

  • Liver damage
  • Accidentally taking too much medication
  • Worsening of certain medical conditions
  • Allergic skin reactions

Prices with our coupons for Phenylephrine vs. Sudafed PE Pressure and Pain

Price Card Drug Icon
Phenylephrine1 eye dropper / 2ml of 2.5%
$21.22$40.99
Get free coupons
More Information
Price Card Drug Icon
Acetaminophen/Phenylephrine56 tablets / 325mg/5mg
$10.50$10.99
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.