Key takeaways
Paroxetine (brand name: Paxil) and buspirone (former brand name: Buspar) are both used to treat anxiety, but they have some key differences. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that also treats depression and other mental health conditions. It works by increasing serotonin levels in the brain and is available in both immediate-release and extended-release forms. Common side effects include nausea, sexual problems, and weight gain. Buspirone, on the other hand, is an antianxiety medication that is not an SSRI. It is typically taken twice a day and is not a first-choice treatment for anxiety. Buspirone's side effects include dizziness, nausea, and headaches, but it has a much lower risk of withdrawal symptoms compared to paroxetine. Additionally, buspirone does not cause significant weight gain. Both are available as lower-cost generics. While paroxetine can take several weeks to show full benefits, buspirone also requires a few weeks to start working. Neither medication is suitable for immediate relief of anxiety symptoms.
