Key takeaways
Onzetra (sumatriptan) and almotriptan are both triptans used to treat migraines, but they have some key differences. Onzetra is a nasal powder that you blow into your nose using a special device, while almotriptan is an oral tablet that you swallow. Onzetra can provide relief within 30 minutes to 2 hours, whereas almotriptan typically works within 2 hours. Onzetra is only available as a brand medication, which can make it more expensive, while almotriptan is available in a generic form, potentially making it more affordable. Onzetra is not recommended for use more than 9 days per month to avoid medication overuse headaches, and the same applies to almotriptan. Additionally, almotriptan can be used in children 12 years or older, while Onzetra is only for adults. Both medications have similar side effects, such as chest pain and high blood pressure, but Onzetra can also cause an unusual taste in your mouth and nasal discomfort.
