Key takeaways
Amlodipine (Norvasc) and losartan (Cozaar) are both medications used to treat high blood pressure, but they belong to different drug classes and work in different ways. Amlodipine is a calcium channel blocker (CCB) that relaxes blood vessels to lower blood pressure and reduce chest pain. It is typically taken once a day and is available in both tablet and liquid forms. Common side effects include swelling and tiredness. On the other hand, Losartan is an angiotensin II receptor blocker (ARB) that also relaxes blood vessels but additionally prevents the body from retaining water and salt. It is also taken once a day. Losartan can cause dizziness and upper respiratory infections. Unlike Amlodipine, Losartan is also used to lower the risk of stroke and slow down the worsening of kidney problems in people with certain health problems. Both medications are not safe to use during pregnancy, but Losartan has a specific warning against use during pregnancy due to potential harm to the unborn baby.
