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Nayzilam vs. Potiga

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nayzilam (midazolam) and ezogabine (Potiga) are both medications used to treat seizures, but they belong to different medication classes and have distinct characteristics. Nayzilam is a benzodiazepine available as a nasal spray, specifically used for treating seizure attacks in people with epilepsy who are 12 years and older. It is a Schedule IV controlled substance and is only available as a brand-name medication. Common side effects include drowsiness, nasal discomfort, and headache. It can interact with opioids, alcohol, and other sedatives, increasing the risk of severe drowsiness and breathing problems. On the other hand, ezogabine was an antiepileptic medication used for partial-onset seizures in adults. However, ezogabine is no longer available in the United States due to low usage, not safety concerns.

Nayzilam

(midazolam)

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Ezogabine

 

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Summary for Nayzilam

Prescription only

Nayzilam (midazolam) is a nasal spray that quickly treats seizure attacks in people with a seizure condition called epilepsy. It comes in a ready-to-use spray device, but the person giving the medication must know when and how to give it properly. Nayzilam (midazolam) commonly causes drowsiness, throat irritation, and nasal discomfort. Nayzilam (midazolam) is only available as a brand-name medication.

Indications for Nayzilam

  • Seizure attacks in people with epilepsy who are 12 years of age and older

Pros and Cons for Nayzilam

Pros

  • Works within 10 minutes to treat seizure attacks
  • Might help prevent another seizure attack from happening within 24 hours
  • Good option for someone who can't take anything by mouth, such as in the middle of a seizure attack

Cons

  • Only for treating seizure attacks, not for long-term seizure control
  • Caregivers need special training to know when and how to give the medication properly.
  • Can't use in children younger than 12 years of age
  • Only available as a brand-name medication

Common Side Effects for Nayzilam

  • Drowsiness (10%)
  • Nasal discomfort (9%)
  • Headache (4%)
  • Throat irritation (3%)
  • Runny nose (3%)

Warnings for Nayzilam

  • Extreme sleepiness and difficulty breathing
  • Misuse and addiction
  • Dependence and withdrawal
  • Suicidal thoughts or behaviors
  • Difficulty with concentration, focus, and memory
  • Rise in eye pressure in people with glaucoma

Summary for Potiga

Discontinued

Ezogabine is a medication used for treating seizures in adults. It's no longer available in the United States, because it was discontinued.

Indications for Potiga

  • Partial-onset seizures

Pros and Cons for Potiga

Pros

Cons

Prices with our coupons for Nayzilam vs. Potiga

Price Card Drug Icon
Nayzilam2 nasal sprays / 5mg
$632.83$812.55
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Potiga30 tablets / 300mg
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