Skip to main content

Compare
Nasonex vs. Astepro

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Nasonex (mometasone) and Astepro (azelastine) are both nasal sprays used to treat allergy symptoms, but they work differently and have some key differences. Nasonex is a corticosteroid that reduces inflammation and is available both over-the-counter (OTC) and by prescription. It can be used for relief of allergy symptoms, prevention of seasonal allergies, and treatment of nasal polyps. Astepro, on the other hand, is an antihistamine that blocks histamine to relieve symptoms like a stuffy or runny nose, sneezing, and itching. Astepro is available OTC and is not a steroid. Nasonex can be used by children as young as 2 years old for OTC use, while Astepro is only approved for children 6 years and older. Nasonex may take 1 to 2 weeks to show full effects, whereas Astepro can start working within 15 to 30 minutes. Additionally, Nasonex does not cause drowsiness, but Astepro might make you feel sleepy. Both medications have side effects, but they differ in type and frequency.

mometasone nasal spray

 

Get free coupons

Astepro Allergy

(azelastine)

Get free coupons

Summary for Nasonex

Prescription or over-the-counter

Mometasone nasal spray is used to prevent the nose symptoms of seasonal allergies, as well as to treat nose and sinus inflammation in adults with nasal polyps. Some side effects this medication can cause include headache and bloody nose. Mometasone nasal spray is available both with a prescription and over the counter (OTC).

Indications for Nasonex

  • Temporary relief of allergy symptoms (e.g., stuffy or runny nose, sneezing, itchy nose) (OTC only)
  • Prevention of seasonal allergies (prescription only)
  • Treatment of long-term nose and sinus inflammation with nasal polyps (prescription only)

Pros and Cons for Nasonex

Pros

  • Works well to prevent and treat allergy symptoms
  • Available OTC
  • Can be used to help control allergy symptoms in children 2 years or older (OTC only)
  • Available as a lower-cost generic with a prescription

Cons

  • Can take 1 to 2 weeks or longer to see the full effects
  • Doesn't have a counter on the spray bottle, so it can be hard to remember how many sprays are left
  • Can cause side effects like headache and nose bleeds in some people
  • Unknown if safe while pregnant or breastfeeding

Common Side Effects for Nasonex

  • Headache (26%)
  • Viral infection (14%)
  • Sore throat (12%)
  • Bloody nose or mucus (11%)
  • Coughing (7%)
  • Upper respiratory tract infection (i.e., common cold; 6%)
  • Period cramps (5%)
  • Muscle pain (5%)
  • Congestion, pressure near the nose or forehead, and other symptoms of sinus infection (5%)

Warnings for Nasonex

  • Nose injury and slowed wound healing
  • Fungal infection in the nose and throat
  • Vision changes
  • Risk of infection
  • Hormone changes
  • Poor growth in children

Summary for Astepro

Over-the-counter

Astepro Allergy (azelastine) is an antihistamine nasal spray that's used to treat nasal symptoms due to allergies, such as stuffy nose, sneezing, and runny nose. Astepro Allergy (azelastine) is available over-the-counter (OTC) for adults and children 6 years and older. The strength of Astepro Allergy (azelastine) is 0.15%. The dosage depends on your age, but it's usually sprayed into the nose once or twice a day. Side effects can include a bitter taste in the mouth, nasal discomfort, and sneezing.

Note: Azelastine nasal spray is also available by prescription in 0.1% and 0.15% strengths.

Indications for Astepro

Short-term relief of nasal symptoms due to allergies:

  • Stuffy nose
  • Runny nose
  • Sneezing
  • Itchy nose

Pros and Cons for Astepro

Pros

  • Available over the counter; doesn't require a prescription
  • Sprayed directly in the nose
  • Can work within 15 to 30 minutes to relieve allergy symptoms

Cons

  • Not approved for children younger than 6 years old
  • Can cause drowsiness
  • Might leave a bitter taste in your mouth

Common Side Effects for Astepro

  • Bitter taste (up to 6%)
  • Nasal discomfort (up to 4%)
  • Nosebleed (up to 2%)
  • Sneezing (up to 2%)

Warnings for Astepro

  • Possible sleepiness and difficulty concentrating

Prices with our coupons for Nasonex vs. Astepro

Price Card Drug Icon
Mometasone1 nasal spray / 17g of 50mcg
$39.19$136.12
Get free coupons
More Information
Price Card Drug Icon
Azelastine Non-Prescription1 nasal spray / 23ml of 205.5mcg/spray
$17.54-
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.