Miralax vs. Colace for Constipation: Important Differences and Potential Risks.

Polyethylene glycol

(Miralax)

Docusate

(Colace)

Summary for Miralax

Over-the-counter

Polyethylene glycol (Miralax) is an over-the-counter (OTC) medication used for occasional constipation. It comes as a powder that you need to mix with a beverage and then drink. Typically, you take a dose of polyethylene glycol (Miralax) once a day, for up to a week. Most people will experience a bowl movement in 1 to 3 days. Some side effects that polyethylene glycol (Miralax) can cause include nausea, bloating, and passing gas.

Indications for Miralax

Occasional constipation and irregular bowel movements

Pros and Cons for Miralax

Pros

Available OTC, so you don't need a prescription from your provider
Causes less cramping, bloating, gas, or feelings of "having to go right now" compared to other laxatives
A possible option during pregnancy, if provider says it's safe for you to take

Cons

Can take a few days before you have a bowel movement
Only for short-term relief of constipation
Might cause loose, watery stools

Common Side Effects for Miralax

Nausea
Passing gas
Bloating

Warnings for Miralax

Complete or partial blockage of intestines

Summary for Colace

Over-the-counter

Docusate, often known by the brand name Colace, is a stool softener that you can find over the counter (OTC). It helps relieve constipation in adults and children. You take this medication by mouth, and it comes as capsules, tablets, and a liquid. The dosage depends on the formulation you have and your age. Side effects aren't common, but some people might have stomach cramps. Even though Colace is a popular brand name, docusate is also sold under many other brand names and as a generic.