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Lopressor vs. Toprol XL

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Metoprolol tartrate

(Lopressor)

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Metoprolol succinate

(Toprol XL)

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Summary for Lopressor

Prescription only

Metoprolol tartrate (Lopressor) is a beta blocker used to treat chest pain and high blood pressure in adults. It can also lower the risk of death after a heart attack. You take it by mouth, typically once or twice a day, but your dose depends on your condition. Side effects include dizziness, shortness of breath, and it can make you tired.

Indications for Lopressor

Pros and Cons for Lopressor

Pros

  • Fast-acting — works quickly after you take it
  • First choice treatment after a heart attack
  • Available in different strengths, so your dose can be adjusted easily
  • Possible option for those who are breastfeeding

Cons

Common Side Effects for Lopressor

  • Tiredness (10%)
  • Dizziness (10%)
  • Diarrhea (5%)
  • Rash (5%)
  • Depression (5%)

Warnings for Lopressor

  • Risks of stopping treatment suddenly
  • Worsening heart failure
  • Risk of difficulty breathing
  • Major surgery
  • Hiding symptoms of low blood sugar
  • Hiding symptoms of overactive thyroid
  • Severe allergic reactions

Summary for Toprol XL

Prescription only

Metoprolol succinate (Toprol XL) is used to treat hypertension and to control chronic (long-term) chest pain. It's also used to lower the risk for hospitalization and death in people with heart failure. Metoprolol succinate (Toprol XL) is the extended-release version of metoprolol tartrate (Lopressor), but keep in mind the two versions don't treat the exact same conditions. And because metoprolol succinate (Toprol XL) is longer-acting, it's taken by mouth typically taken just once daily. Some common side effects of metoprolol succinate (Toprol XL) include tiredness or dizziness.

Indications for Toprol XL

  • High blood pressure
  • Chest pain (angina)
  • Lower the risk of hospitalization and death in heart failure

Pros and Cons for Toprol XL

Pros

  • A first-choice option to prevent chest pains (angina)
  • A first-choice option for heart failure
  • Only needs to be taken once a day
  • Available as capsules (Kapspargo) that can be opened and sprinkled on soft foods, good for people who've trouble swallowing pills

Cons

Common Side Effects for Toprol XL

  • Tiredness
  • Dizziness
  • Depression
  • Diarrhea
  • Trouble catching your breath
  • Drop in heart rate
  • Rash

Please note: The side effects above occurred in 2% or more of people taking metoprolol succinate (Toprol XL).

Warnings for Toprol XL

  • Heart problems after suddenly stopping the medication
  • Worsened symptoms of heart failure
  • Risk of difficulty breathing
  • Rise in blood pressure in people with pheochromocytoma
  • Greater risk during surgery
  • Hiding symptoms of low blood sugar
  • Masked symptoms of overactive thyroid

Prices with our coupons for Lopressor vs. Toprol XL

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Metoprolol60 tablets / 25mg
$9.00$9.00
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Metoprolol ER90 tablets / 25mg
$15.75$101.54
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