Skip to main content

Compare
Lantus vs. Apidra

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Lantus (insulin glargine) and Apidra (insulin glulisine) are both insulins used to manage blood sugar levels in people with diabetes, but they have some key differences. Lantus is a long-acting insulin that is typically injected once daily and helps control blood sugar levels for about 24 hours. In contrast, Apidra is a rapid-acting insulin that starts working within 15 minutes and is usually taken before or right after meals to manage blood sugar spikes. Lantus is used for both Type 1 and Type 2 diabetes in adults and children, while Apidra is used for Type 1 diabetes in children aged 4 and older and for Type 2 diabetes in adults. Apidra can also be administered through an insulin pump or an IV injection in a hospital setting, whereas Lantus is only given as a subcutaneous injection. Both medications can cause low blood sugar and weight gain, but Apidra needs to be taken multiple times a day, which might be less convenient than the once-daily dosing of Lantus.

Lantus

(insulin glargine)

Get free coupons

Apidra

(insulin glulisine)

Get free coupons

Summary for Lantus

Prescription only

Lantus (insulin glargine) is a type of long-acting insulin. It's used to help manage blood sugar levels in people with Type 1 diabetes or Type 2 diabetes. Lantus (insulin glargine) is injected under the skin once daily. Your dose will depend on a few things, such as the type of diabetes you have and your blood sugar levels. This medication comes in a vial (Lantus) as well as in a prefilled insulin pen (Lantus Solostar). Some side effects include upper respiratory tract infections. It can also cause redness and swelling at the injection site.

Indications for Lantus

Pros and Cons for Lantus

Pros

  • Helps keep your blood sugar controlled for about 24 hours
  • Injected once daily
  • Approved for both adults and children
  • Available as a vial and prefilled pen

Cons

  • Given as an injection under the skin
  • Has a risk of causing dangerously low blood sugar
  • Might cause weight gain
  • Can't be mixed with other insulins within the same syringe

Common Side Effects for Lantus

Type 1 diabetes

Type 2 diabetes

  • Upper respiratory tract infection (11%)
  • Other infection (10%)
  • Eye problem (6%)

Warnings for Lantus

  • Risk of infection from sharing pens and needles
  • Risk of changes to blood sugar levels with changes to your insulin routine
  • Low blood sugar (hypoglycemia)
  • Low potassium levels
  • Swelling and risk of heart failure when using with certain diabetes medications
  • Severe allergic reaction

Summary for Apidra

Prescription only

Insulin glulisine is a rapid-acting insulin that's available as a vial (Apidra) and a pre-filled pen (Apidra Solostar). It's used to control blood sugar from meals for people with either Type 1 diabetes (T1D) or Type 2 diabetes (T2D). Apidra (insulin glulisine) is given under the skin as either a quick injection or continuously through an insulin pump. It can also be given as an injection through the veins (IV) for people in the hospital. Side effects include low blood sugar (hypoglycemia) and common cold symptoms.

Indications for Apidra

Pros and Cons for Apidra

Pros

  • Works within 15 minutes to lower blood sugar
  • Available as a prefilled pen, which might be easier to use than the vial
  • Can be used with some insulin pumps
  • Can be mixed with NPH insulin (e.g., Novolin N), if instructed by your care team

Cons

  • Raises risk of dangerously low blood sugar levels
  • Given as an injection
  • Might need to inject multiple times a day
  • Might cause weight gain

Common Side Effects for Apidra

Type 1 diabetes

Type 2 diabetes

  • Upper respiratory tract infection (up to 11%)
  • Common cold (8%)
  • Swelling in the hands, ankles, or legs (8%)
  • Flu (6%)
  • Joint pain (6%)

Warnings for Apidra

  • Spread of infections from sharing injection supplies
  • Risk of high and low blood sugar levels
  • Dangerously low blood sugar levels (hypoglycemia)
  • Allergic reaction
  • Low blood potassium levels
  • Swelling from fluid buildup and risk of heart failure
  • Dangerously high blood sugar levels or buildup of ketones (for people who use insulin pump)

Prices with our coupons for Lantus vs. Apidra

Price Card Drug Icon
Lantus1 carton / 5 solostar pens of 3ml
$35.00-
Get free coupons
More Information
Price Card Drug Icon
Apidra1 carton / 5 solostar pens of 3ml
$168.84$201.95
Get free coupons
More Information

Browse medications by letter

Show All

Browse prescription and over-the-counter medications from A to Z, compare drug prices, and start saving.