Key takeaways
Ivermectin (Stromectol) and metronidazole (Flagyl) are both used to treat parasitic infections, but they belong to different medication classes. Ivermectin is an antiparasitic agent, while metronidazole is a nitroimidazole antibiotic. Ivermectin is FDA-approved for treating strongyloidiasis and river blindness, and it is sometimes used off-label for scabies. Metronidazole is used for a variety of bacterial and parasitic infections, including trichomoniasis and amebiasis. Ivermectin is typically taken as a single dose based on body weight, whereas metronidazole is usually taken multiple times a day for several days. Both medications are available as lower-cost generics. Common side effects of ivermectin include stomach pain and nausea, while metronidazole can cause headaches and a metallic taste. Both medications can interact with warfarin, and metronidazole should not be taken with alcohol or disulfiram due to serious interactions.
