Key takeaways
Galantamine (Razadyne ER) and memantine (Namenda) are both prescription medications used to treat Alzheimer's disease, but they work differently and are used for different stages of the condition. Galantamine is an acetylcholinesterase inhibitor used for mild-to-moderate Alzheimer's, while memantine is an NMDA antagonist used for moderate-to-severe Alzheimer's. Galantamine helps by preventing the breakdown of acetylcholine, a chemical important for memory and learning, whereas memantine works by reducing the activity of certain brain chemicals to prevent nerve damage. Galantamine is available in immediate-release tablets, oral solution, and extended-release capsules, while memantine comes in immediate-release tablets, oral solution, and extended-release capsules. Common side effects of either medication include nausea, dizziness, and diarrhea. Galantamine should be taken with food to reduce stomach upset, but memantine can be taken with or without food. Both medications require careful dosing adjustments, especially if you have kidney problems.
