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Compare Foundayo vs. Wegovy

Head-to-head comparisons of medication uses, side effects, warnings, and more.

  • Foundayo (orforglipron)
    Wegovy (semaglutide)
  • Foundayo (orforglipron)
    Wegovy (semaglutide)

  • Summary of Foundayo vs. Wegovy

    Summary for GLP-1 agonist
    Prescription only

    Foundayo (orforglipron) is an oral glucagon-like peptide-1 (GLP-1) receptor agonist. It's approved for weight loss in certain adults. This medication is meant to be used together with a reduced-calorie diet and exercise. Foundayo (orforglipron) comes as tablets and is taken by mouth once a day with or without food. The dose is slowly raised over several weeks. Common side effects include nausea, constipation, and diarrhea.

    Summary for GLP-1 agonist
    Prescription only

    Wegovy (semaglutide) is a glucagon-like peptide-1 (GLP-1) receptor agonist. It comes in prefilled pens you use to inject the medication under the skin once a week. Wegovy (semaglutide) also comes as tablets that are swallowed once a day. This medication is approved for weight loss in some people. It can help lower the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease. The pens are also approved for certain adults with a liver problem called metabolic dysfunction-associated steatohepatitis (MASH). The medication works best when taken with a lower-calorie diet and regular exercise. Side effects include nausea, diarrhea, and stomach pain.

  • Indications of Foundayo vs. Wegovy

    Indications for
    •Weight loss and long-term weight management in adults who are considered obese or overweight with at least one weight-related condition
    Indications for

    Injectable pens:

    •

    Weight loss and long-term weight management in:

    •People ages 12 years and older who are considered obese
    •Adults considered overweight with at least one weight-related condition (e.g., high blood pressure, Type 2 diabetes, high cholesterol)
    •

    Lowering the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease

    •

    Metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate-to-advanced liver scarring, but not cirrhosis

    Tablets:

    •Weight loss and long-term weight management in adults who are considered obese or overweight with at least one weight-related condition
    •Lowering the risk of heart attack, stroke, and death due to heart problems in adults with a larger body size and heart disease

  • Pros and Cons of Foundayo vs. Wegovy

    Pros and Const for GLP-1 agonist
    Pros
    •A pill that's taken once a day at any time of day
    •Can take with or without food
    Cons
    •Can cause nausea, diarrhea, and stomach pain
    •Not approved for children
    Pros and Const for GLP-1 agonist
    Pros
    •Available as once-weekly injectable pens and as once-daily pills
    •Injectable pens approved for weight loss in children ages 12 years and older considered obese
    Cons
    •Can cause stomach pain, nausea, and diarrhea
    •Can't take with other semaglutide products (Ozempic, Rybelsus) or with other GLP-1 agonists

  • Common Side Effects of Foundayo vs. Wegovy

    Common Side Effects for
    •Nausea (26-35%)
    •Constipation (20-27%)
    •Diarrhea (21-25%)
    •Vomiting (13-24%)
    •Indigestion (12-16%)
    •Stomach pain (13-14%)
    •Headache (8-9%)
    •Bloating (7-9%)
    •Feeling tired (6-9%)
    •Belching (6-8%)
    •Gastroesophageal reflux disease (GERD; 6-7%)
    •Having a lot of gas (5-6%)
    •Hair loss (4-5%)
    Common Side Effects for
    •Nausea (44%)
    •Diarrhea (30%)
    •Vomiting (24%)
    •Constipation (24%)
    •Stomach pain (20%)
    •Headache (14%)
    •Tiredness (11%)

  • Warnings of Foundayo vs. Wegovy

    Common Side Effects for
    •Possible risk of thyroid cancer
    •Severe stomach side effects
    •Kidney damage
    •Inflammation of the pancreas (pancreatitis)
    •Gallbladder problems
    •Low blood sugar
    •Allergic reactions
    •Eye problems in people with Type 2 diabetes (diabetic retinopathy)
    •Lung problems during general anesthesia or deep sedation
    Common Side Effects for
    •Possible risk for thyroid cancer
    •Inflammation of the pancreas (pancreatitis)
    •Gallbladder problems
    •Low blood sugar
    •Kidney damage
    •Allergic reactions
    •Eye problems in people with Type 2 diabetes (diabetic retinopathy)
    •Faster heart rate
    •Lung problems during general anesthesia or deep sedation

  • Prices with our coupons for Foundayo vs. Wegovy

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    Learn more about Wegovy

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