Key takeaways
Flonase (fluticasone) and Advil Allergy and Congestion Relief (ibuprofen/phenylephrine/chlorpheniramine) are both used to treat allergy symptoms, but they work differently and are used in different ways. Flonase is a corticosteroid nasal spray that reduces inflammation in your nose to relieve symptoms like congestion, runny nose, and sneezing. It is available both as a prescription and over-the-counter (OTC) medication and must be used daily for the best results. On the other hand, Advil Allergy and Congestion Relief is a combination of an antihistamine (chlorpheniramine), a non-steroidal anti-inflammatory drug (NSAID) ibuprofen, and a decongestant (phenylephrine). Studies show oral phenylephrine isn't an effective decongestant. This makes Advil Allergy and Congestion Relief not the best option to relieve congestion. It is taken orally and provides short-term relief for a wide range of symptoms, including minor aches and pains. Unlike Flonase, which is used once daily, Advil Allergy and Congestion Relief can be taken every 4 hours. Additionally, Flonase can be used in children as young as 2 years old (for certain formulations), while Advil Allergy and Congestion Relief is not recommended for children under 12 years old.
