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Claritin vs. Claritin-D

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Loratadine (Claritin) and loratadine/pseudoephedrine (Claritin-D) are both over-the-counter medications used to relieve allergy symptoms, but they have some key differences. Loratadine is an antihistamine that helps with symptoms like runny nose, itchy eyes, and sneezing. It is available in various forms, including tablets and oral solutions, and is typically taken once a day. On the other hand, Claritin-D combines loratadine with pseudoephedrine, a decongestant that also relieves nasal and sinus congestion. Claritin-D comes in 12-hour and 24-hour tablets, which are taken once or twice a day, respectively. Loratidine can cause drowsiness, while Claritin-D can cause side effects like high blood pressure and fast heart rate due to the pseudoephedrine. Additionally, Claritin-D is kept behind the pharmacy counter and requires you to show ID to purchase it. If you have heart problems or high blood pressure, you should consult a healthcare professional before taking Claritin-D.

Loratadine

(Claritin)

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Claritin-D

(loratadine / pseudoephedrine)

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Summary for Claritin

Over-the-counter

Loratadine (Claritin) is an over-the-counter antihistamine for adults and kids. It helps relieve allergy symptoms like a runny nose, sneezing, and watery eyes. This allergy medication is taken by mouth, usually once a day. It comes as different formulations, including regular tablets, chewable tablets, and a liquid. Loratadine (Claritin) is a non-drowsy allergy medication because it's less likely to make you sleepy. Other side effects can include headache and feeling tired. Loratadine (Claritin) is available as a brand-name and generic.

Indications for Claritin

  • Short-term relief of allergy symptoms (runny nose, itchy nose or throat, itchy or watery eyes)

Pros and Cons for Claritin

Pros

Cons

  • Can take 1 to 3 hours to start working
  • Regular tablets and quick-dissolving tablets not for children younger than 6
  • Might have a higher risk of side effects if you have liver or kidney problems

Common Side Effects for Claritin

  • Headache (12%)
  • Sleepiness (8%)
  • Feeling tired (4%)
  • Dry mouth (3%)

Warnings for Claritin

  • Sleepiness
  • Accidentally taking too much medication
  • Caution use in people with phenylketonuria (PKU) - chewable tablets and orally disintegrating tablets

Summary for Claritin-D

Over-the-counter

Claritin-D (loratadine / pseudoephedrine) is an over-the-counter medication that's used to relieve allergies and congestion. It's available as a 24-hour tablet that's taken once per day and a 12-hour tablet that's taken twice per day. Possible side effects include headache, dry mouth, drowsiness, and difficulty sleeping. There are lower-cost generic and brand versions of the medication available. You can find Claritin-D (loratadine / pseudoephedrine) at the pharmacy counter (or behind the counter).

Indications for Claritin-D

Short-term relief of allergy symptoms:

  • Runny nose
  • Itchy nose or throat
  • Itchy or watery eyes
  • Stuffy nose
  • Nasal congestion
  • Sinus congestion or pressure

Pros and Cons for Claritin-D

Pros

  • Easier to take a combination pill instead of two separate pills for congestion and other allergy symptoms
  • Available as a once-daily tablet
  • Available over the counter

Cons

  • More difficult to customize the dose since Claritin-D (loratadine / pseudoephedrine) is a combination of two medications
  • Not the best choice for people who have difficulty swallowing tablets (can't crush the tablets and no available liquid form available)
  • Can't be used in children younger than 12 years

Common Side Effects for Claritin-D

  • Headache (25%)

Warnings for Claritin-D

  • Fast heart rate and high blood pressure
  • Possible drowsiness
  • Worsening of medical conditions
  • Accidental overdose

Prices with our coupons for Claritin vs. Claritin-D

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Loratadine30 tablets / 24 hour
$8.59$8.93
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Price Card Drug Icon
Loratadine/Pseudoephedrine30 tablets / 24 hour
$22.38$47.59
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