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Cipro vs. Isoniazid

Head-to-head comparisons of medication uses, side effects, warnings, and more.

Key takeaways

Ciprofloxacin (Cipro) and isoniazid are both antibiotics, but they treat different types of infections and belong to different drug classes. Ciprofloxacin (Cipro) is a fluoroquinolone antibiotic used to treat various bacterial infections like sinus infections, UTIs, and anthrax exposure. It works by blocking enzymes that bacteria need to grow. Isoniazid, on the other hand, is an antitubercular agent specifically used to treat and prevent tuberculosis (TB). It kills TB bacteria by stopping them from making their protective covering. Ciprofloxacin (Cipro) is taken twice daily and can cause serious side effects like tendon rupture and nerve damage, while isoniazid is usually taken once daily and can cause serious liver injury. Additionally, isoniazid interacts with many foods and medications, requiring you to avoid certain foods like cheese and red wine. Both medications are available in generic forms and require a prescription.

Ciprofloxacin

(Cipro)

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Isoniazid

 

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Summary for Cipro

Prescription only

Ciprofloxacin (Cipro) is a fluoroquinolone antibiotic. It can treat many types of bacterial infections, including sinus infections and urinary tract infections (UTIs). But because ciprofloxacin (Cipro) can cause serious side effects, such as tendon rupture and nerve damage, it's usually only prescribed for more serious infections or when there aren't any safer options. Ciprofloxacin (Cipro) is taken by mouth, typically twice daily. It's available as a pill and oral solution. Some of the more common side effects of this medication include nausea and diarrhea.

Indications for Cipro

Adults only

Adults and children

Pros and Cons for Cipro

Pros

  • Can take with or without food
  • Available as tablets, oral liquid, and injection
  • Possible option for people with penicillin allergy

Cons

Common Side Effects for Cipro

  • Nausea
  • Diarrhea
  • Vomiting
  • Rash
  • Abnormal liver blood test results

Warnings for Cipro

  • Tendon inflammation and rupture
  • Effects on the brain, nerves, and mental health
  • Worsening of myasthenia gravis
  • Severe allergic and skin reactions
  • Liver damage
  • Severe damage to a major blood vessel
  • Infectious diarrhea
  • Life-threatening abnormal heart rhythm (QT prolongation)
  • Muscle, bone, or joint problems in children
  • Sun and light sensitivity
  • Kidney problems

Summary for Isoniazid

Prescription only

Isoniazid is an antimycobacterial agent for treating and preventing tuberculosis (TB) in children and adults. It's available as a generic oral tablet and solution, usually taken daily or a few times a week, depending on your dose. For treating active TB, you'll likely need to take it along with other TB medications (like rifampin, pyrazinamide, and ethambutol) to prevent antibiotic resistance. Serious side effects include severe liver injury. It's also known to interact with many foods and medications.

Indications for Isoniazid

Pros and Cons for Isoniazid

Pros

  • Is one of the main medications used to treat TB
  • Can be taken by itself for prevention of TB (along with a pyridoxine supplement)
  • Available as an oral tablet and oral solution
  • Available as a lower-cost generic

Cons

  • Can cause serious liver damage
  • Likely will need to take it for many months
  • You might need to take each dose in front of a healthcare professional
  • Interacts with many foods and medications

Common Side Effects for Isoniazid

  • Tingling or numbness in your hands and feet
  • Rise in liver enzymes

Warnings for Isoniazid

  • Liver injury (hepatitis)
  • Interactions

Prices with our coupons for Cipro vs. Isoniazid

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Ciprofloxacin14 tablets / 500mg
$10.88$13.08
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Isoniazid30 tablets / 300mg
$12.27$126.99
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