Key takeaways
Cefixime (Suprax) and cefdinir (formerly Omnicef) are both cephalosporin antibiotics used to treat bacterial infections. They share some common uses, such as treating ear infections and strep throat. However, cefdinir is also used for pneumonia and sinus infections, while cefixime is approved for urinary tract infections and gonorrhea. Cefixime is available as a tablet, chewable tablet, and suspension, while cefdinir comes in capsules and suspension forms. Cefixime is typically taken once a day, but cefdinir can be taken once or twice a day depending on the infection. Both medications can cause diarrhea, nausea, and rash. Cefdinir has specific interactions with antacids and iron supplements, which should be taken at different times to avoid absorption issues. Both medications are available as generics, but cefixime tends to be more expensive. If you have a penicillin allergy, you should be cautious with both medications due to potential cross-reactivity.
