Key takeaways
Cefdinir (Omnicef) and amoxicillin (Amoxil) are both antibiotics used to treat bacterial infections, such as sinus infections, ear infections, and strep throat. However, they belong to different medication classes. Cefdinir is a cephalosporin antibiotic, while amoxicillin is a penicillin antibiotic. Cefdinir is available as capsules and an oral suspension, and it can be taken once or twice a day. Amoxicillin comes in tablets, capsules, a liquid, and chewable tablets, and it may need to be taken up to three times a day. Both medications can cause side effects like diarrhea and rash, but amoxicillin can also cause vomiting and taste changes. Both medications can interact with warfarin, while Cefdinir has specific interactions with antacids and iron supplements. Additionally, cefdinir is sometimes used off-label for urinary tract infections (UTIs), whereas amoxicillin is FDA-approved for UTIs but not always the first choice. Both medications require a prescription and should be taken as directed by your healthcare provider.
