Key takeaways
Benzoyl peroxide and tetracycline are both used to treat acne, but they work in different ways and have different uses. Benzoyl peroxide is an antiseptic available over-the-counter in various forms like gels, creams, and lotions. It works by preventing acne-causing bacteria from growing on your skin. Tetracycline, on the other hand, is a prescription-only antibiotic that treats a wide range of bacterial infections, including severe acne, by stopping bacteria from multiplying in your body. Benzoyl peroxide is applied topically, while tetracycline is taken orally. Benzoyl peroxide can cause skin irritation and is not recommended for people with sensitive skin, whereas tetracycline can cause stomach issues and is not safe for young children or pregnant women. Additionally, tetracycline can make your skin more sensitive to sunlight and can interact with certain foods and medications, while benzoyl peroxide can bleach hair and clothing.
