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Benadryl vs. Dramamine

Diphenhydramine, also known by the brand name Benadryl, is an over-the-counter antihistamine used to relieve allergy or common cold symptoms in adults and children. It comes as pills and a liquid and is typically taken by mouth every 4 to 6 hours as needed. Because it can make you drowsy, some people also use it as a sleep aid at bedtime. Common side effects include sleepiness, dizziness, and dry mouth.

• Short-term relief of allergy or common cold symptoms (runny nose, sneezing, itchy nose or throat, and itchy or watery eyes) - people 6 years and older
• Occasional trouble sleeping - people 12 years and older

• Sleepiness
• Dizziness
• Constipation
• Blurry vision
• Dry mouth

• Sleepiness
• Accidental overdose
• Worsening of certain health problems

Dimenhydrinate is an over-the-counter medication that helps prevent and treat nausea, vomiting, or dizziness from motion sickness. It's a type of antihistamine and anticholinergic medication. It has many brand names, including Dramamine and Dramamine For Kids, and is also available as a generic. Dimenhydrinate comes as tablets, chewable tablets, and a syrup. The dosage depends on your age and the form of the medication you're using. It's usually taken a few times a day as needed. Side effects include feeling drowsy, dizzy, and constipated.

• Prevention and treatment of nausea, vomiting, or dizziness from motion sickness

• Sleepiness
• Dizziness
• Dry mouth
• Constipation
• Blurry vision

• Sleepiness
• Worsening of certain medical conditions
• Accidentally taking too much medication (accidental overdose)
• Use with caution in people with phenylketonuria (PKU) - chewable tablets only