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Amlodipine vs. Losartan

Amlodipine tablets, also known as the brand name Norvasc, help treat high blood pressure in adults and children. It can also help with coronary artery disease, including related angina or chest pain. This medication belongs to the drug class called calcium channel blockers. The tablets are taken by mouth once a day. Some side effects can include tiredness and swelling of the hands and feet.

• High blood pressure
• Coronary artery disease, including some types of chest pain (angina)

• Tiredness (5%)
• Nausea (3%)

• Low blood pressure
• Worsening chest pain and risk of heart attack

Losartan, also known by the brand name Cozaar, is a first-choice medication that's used to lower blood pressure. It's also shown to protect against stroke in certain people. In addition, this medication can slow down the worsening of kidney problems in certain people with diabetes. Losartan (Cozaar) belongs to the drug class called angiotensin II receptor blockers (ARBs). This medication is taken by mouth once daily and is available as a lower-cost generic. Side effects can include dizziness, fatigue, and upper respiratory infections.

• High blood pressure
• Lower the risk of stroke in people with high blood pressure who have a thickened heart (left ventricular hypertrophy)
• Slow down the worsening of kidney problems in people with Type 2 diabetes and high blood pressure

• Upper respiratory infection (e.g., common cold; 8%)
• Dizziness (3%)
• Stuffy nose (2%)
• Back pain (2%)

• Harm to unborn baby
• Low blood pressure
• Kidney damage
• High potassium levels