Key takeaways
Belsomra (suvorexant) and Ambien (zolpidem) are both used to treat insomnia. Belsomra is an orexin receptor antagonist that can help you fall asleep and stay asleep. Ambien is a sedative that slows brain activity. The immediate-release version helps you fall asleep. The extended-release version can help you fall asleep and stay asleep. Belsomra is typically taken 30 minutes before bedtime on an empty stomach. Ambien is also taken once a night but can be taken with or without food. It can also be used on an as-needed basis. Belsomra is only available as a brand-name medication, while Ambien is available as a generic. Both medications are only meant for short-term use because they’re controlled substances that can cause dependence and misuse. They can also cause unusual behaviors such as sleepwalking.
