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Byetta

Byetta Side Effects

Daisy Chau, PharmDKristianne Hannemann, PharmD
Reviewed by Daisy Chau, PharmD, Kristianne Hannemann, PharmD
Last reviewed on August 13, 2026

The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.

Common Side Effects

  • Nausea (up to 44%)
  • Vomiting (up to 18%)
  • Diarrhea (up to 18%)
  • Headache (up to 14%)
  • Constipation (Up to 10%)

Note: Side effects can vary depending on whether exenatide is taken alone or with other diabetes medications.

Less Common Side Effects

  • Indigestion
  • Weakness
  • Dizziness
  • Feeling jittery
  • Excessive sweating
  • Low blood sugar
  • Tiredness
  • Injection-site reactions
  • Smaller appetite

Byetta serious side effects

Contact your healthcare provider immediately if you experience any of the following.

  • Inflammation of the pancreas (pancreatitis): stomach or back pain that won't go away, vomiting
  • Low blood sugar: dizziness or lightheadedness, sweating, confusion or drowsiness, headache, blurred vision, slurred speech, shakiness, fast heartbeat, anxiety or irritability, hunger, weakness, feeling jittery
  • Kidney problems: changes in urination, swollen feet or ankles, tiredness, nausea
  • Severe stomach problems: nausea, vomiting, diarrhea, bloating
  • Serious bleeding problems: unusual bleeding, bleeding when you brush your teeth, easy bruising, pinpoint red spots on the skin
  • Serious allergic reaction: rash, hives, trouble breathing, swelling of the face or throat, itching, fainting or feeling dizzy, fast heartbeat
  • Gallbladder problems: pain in the upper stomach, fever, yellowing of the whites of the eyes, clay-colored stool
When do Byetta possible side effects begin and end?
Time passed since treatment started:
H
D
W
M
Diarrhea
Nausea
Vomiting
Injection site reactions

Source: DailyMed

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