
bromfenac
BromSite (bromfenac 0.075%) is a prescription eye drop. It's used to relieve eye pain and inflammation after adults get cataract surgery. It's a type of medication called a nonsteroidal anti-inflammatory drug (NSAID). The typical dose is 1 drop into the affected eye twice a day. Side effects include eye pain, blurry vision, and headache. This eye drop is available as a brand-name and generic medication.
What is BromSite?
What is BromSite used for?
- Eye pain and eye inflammation after cataract surgery in adults
How BromSite works
BromSite is a nonsteroidal anti-inflammatory drug (NSAID) that's used as an eye drop. It works by blocking a protein in your body that plays a role in causing inflammation.
When you put BromSite in your eye, it helps relieve eye pain, swelling, and inflammation. This helps your eye heal after cataract surgery.
Drug facts
| Common Brands | BromSite |
|---|---|
| Drug Class | NSAID |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription only |
Side effects of BromSite
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Eye pain (up to 8%)
- Eye floaters (up to 8%)
- Higher eye pressure (up to 8%)
- Headache (up to 8%)
Less Common Side Effects
- Eye redness
- Blurry vision
- Sensitivity to light
BromSite serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: hives; rash; blisters; swelling around the eye; swelling of the face, lips, or tongue; trouble breathing
The following BromSite side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Blurred vision
change in color vision
decreased vision or other changes in vision
difficulty seeing at night
red, sore eyes
sensitivity to light
tearing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abnormal sensation in the eye
burning or stinging of the eye
feeling of having something in the eye
headache
itching of the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of BromSite
Pros
- Works well to help prevent pain and inflammation from cataract surgery
- Can start to feel pain relief within a day
Cons
- Must use twice a day
- Can slow healing for some people
Pharmacist tips for BromSite
- Use BromSite twice a day (once in the morning and again in the evening). Start using the eye drops 1 day before your cataract surgery. Keep using them on the day of the surgery and also every day for the next 2 weeks. This helps reduce eye pain and inflammation after surgery.
- Wash your hands well before using BromSite. Don't touch the dropper tip with your hands or let it touch your eye or any other surface. This helps keep germs out of the bottle and lowers your risk of an eye infection.
- If you wear contact lenses, take them out before using BromSite. The eye drops contain a preservative that can damage your contacts. Wait at least 10 minutes before putting your contact lenses back in.
- How to use BromSite: Tilt your head back and gently pull down your lower eyelid to make a small pocket. Hold the bottle upside down over your eye and squeeze 1 drop into the pocket. Then, close your eye and gently press the inner corner near your nose for a minute. This helps keep the medication in your eye.
- If you use other eye drops with BromSite: Wait at least 5 minutes between each eye medication. This helps each medication stay in your eye long enough to work.
- How to store BromSite: Keep the bottle of BromSite at room temperature between 59ºF and 77ºF.
- If you're pregnant or planning to become pregnant: Talk to your eye specialist. Only a small amount of BromSite is absorbed into your body since it's an eye drop. But NSAIDs like BromSite aren't usually recommended during pregnancy because they can harm an unborn baby. Your eye specialist can help decide if another medication is a better choice for you.
Risks and warnings for BromSite
BromSite can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Allergic reaction
- Risk factors: Sensitive to aspirin or other NSAIDs
Let your prescriber know if you've ever had a reaction to aspirin or other NSAIDs. It's possible that you might have a similar reaction to BromSite.
Stop using BromSite and get medical help right away if you have an allergic reaction to the medication. Watch for rash, hives, swelling around the eye or face, or trouble breathing.
Slower healing
- Risk factors: Also using steroid eye drops
BromSite can slow how fast your eye heals after cataract surgery. Your eye might heal even more slowly if you also need to use steroid eye drops, like prednisolone (Pred Forte). Talk to your eye specialist if you're worried about how your eye is healing.
Bleeding in the eye
- Risk factors: History of bleeding problems | Taking other medications that raise your risk of bleeding
BromSite can raise your risk of bleeding in your eye after eye surgery. Tell your eye specialist if you have a bleeding problem. Also tell them if you take medications that can make you more likely to bleed, such as blood thinners. Call your eye specialist if you notice blood spots on your eye, especially if you've just had eye surgery.
Problems with the cornea
- Risk factors: History of problems with the cornea | Dry eye | Multiple eye surgeries | Complicated eye surgery | Rheumatoid arthritis | Diabetes | Using BromSite for a long time
BromSite eye drops can cause problems with your cornea, the clear front part of your eye. They can include inflammation (called keratitis), corneal thinning, injury, or ulcers. Rarely, these problems can affect your vision. Tell your eye specialist if you've had cornea problems or several eye surgeries in the past. They can help check your risk of cornea problems.
Use BromSite exactly as prescribed. Don't use it longer than prescribed before or after surgery. This helps lessen your risk of cornea problems. Call your optometrist or ophthalmologist right away if you notice changes in your vision, worse eye pain, or more eye irritation.
Remove contact lenses before using BromSite
BromSite contains a preservative that can damage contact lenses. If you wear contact lenses, take them out each time before placing BromSite drops in your eye. You'll need to wait at least 10 minutes before you put your contacts back in.
BromSite dosage
| Dosage | Quantity | Price as low as | Price per unit |
|---|---|---|---|
| 5ml of 0.075% | 1 eye dropper | $70.80 | $70.80 |
Typical dosage for BromSite
The typical dose is 1 drop into the affected eye twice a day (in the morning and evening). Start the day before cataract surgery and then continue for 2 weeks after the surgery.
Interactions between BromSite and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abciximab
- Aceclofenac
- Acemetacin
- Acenocoumarol
- Amiloride
- Amineptine
- Amitriptyline
- Amitriptylinoxide
- Amoxapine
- Amtolmetin Guacil
- Anagrelide
- Apixaban
- Ardeparin
- Argatroban
- Aspirin
- Balsalazide
- Bemiparin
- Bendroflumethiazide
- Benzthiazide
- Betamethasone
- Betrixaban
- Bismuth Subsalicylate
- Bivalirudin
- Budesonide
- Bufexamac
- Bumetanide
- Cangrelor
- Celecoxib
- Certoparin
- Chlorothiazide
- Chlorthalidone
- Choline Magnesium Trisalicylate
- Choline Salicylate
- Cilostazol
- Citalopram
- Clomipramine
- Clonixin
- Clopamide
- Clopidogrel
- Cortisone
- Cyclopenthiazide
- Cyclosporine
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Deflazacort
- Desipramine
- Desirudin
- Desmopressin
- Desvenlafaxine
- Dexamethasone
- Dexibuprofen
- Dexketoprofen
- Diazoxide
- Dibenzepin
- Diflunisal
- Digoxin
- Dipyridamole
- Dipyrone
- Dothiepin
- Doxepin
- Droxicam
- Duloxetine
- Edoxaban
- Enoxaparin
- Eplerenone
- Epoprostenol
- Eptifibatide
- Escitalopram
- Ethacrynic Acid
- Etodolac
- Etofenamate
- Etoricoxib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Feverfew
- Floctafenine
- Flufenamic Acid
- Fluocortolone
- Fluoxetine
- Flurbiprofen
- Fluvoxamine
- Fondaparinux
- Furosemide
- Ginkgo
- Gossypol
- Heparin
- Hydrochlorothiazide
- Hydrocortisone
- Hydroflumethiazide
- Ibuprofen
- Iloprost
- Imipramine
- Indapamide
- Inotersen
- Ketoprofen
- Lepirudin
- Levomilnacipran
- Lithium
- Lofepramine
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Magnesium Salicylate
- Meadowsweet
- Meclofenamate
- Mefenamic Acid
- Melitracen
- Meloxicam
- Mesalamine
- Methotrexate
- Methyclothiazide
- Methylprednisolone
- Metolazone
- Milnacipran
- Morniflumate
- Nabumetone
- Nadroparin
- Naproxen
- Nefazodone
- Nepafenac
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nortriptyline
- Olsalazine
- Opipramol
- Oxaprozin
- Oxyphenbutazone
- Paramethasone
- Parecoxib
- Parnaparin
- Paroxetine
- Pemetrexed
- Pentosan Polysulfate Sodium
- Pentoxifylline
- Phenindione
- Phenprocoumon
- Phenylbutazone
- Phenyl Salicylate
- Piketoprofen
- Piroxicam
- Polythiazide
- Prasugrel
- Prednisolone
- Prednisone
- Proglumetacin
- Propyphenazone
- Proquazone
- Protein C
- Protriptyline
- Reboxetine
- Reviparin
- Rivaroxaban
- Rofecoxib
- Salicylamide
- Salicylic Acid
- Salsalate
- Sertraline
- Sibutramine
- Sodium Salicylate
- Spironolactone
- Sulfasalazine
- Sulindac
- Tacrolimus
- Tenofovir Disoproxil Fumarate
- Tenoxicam
- Tianeptine
- Tiaprofenic Acid
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Tolfenamic Acid
- Tolmetin
- Torsemide
- Trazodone
- Treprostinil
- Triamterene
- Trichlormethiazide
- Trimipramine
- Trolamine Salicylate
- Valdecoxib
- Venlafaxine
- Vilazodone
- Vorapaxar
- Vortioxetine
- Warfarin
- Xipamide
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Alacepril
- Anisindione
- Atenolol
- Azilsartan
- Azilsartan Medoxomil
- Benazepril
- Betaxolol
- Bisoprolol
- Candesartan Cilexetil
- Captopril
- Carteolol
- Carvedilol
- Celiprolol
- Dicumarol
- Enalapril
- Enalaprilat
- Eprosartan
- Esmolol
- Fosinopril
- Irbesartan
- Labetalol
- Levobunolol
- Lisinopril
- Losartan
- Metipranolol
- Metoprolol
- Moexipril
- Nadolol
- Nebivolol
- Olmesartan Medoxomil
- Oxprenolol
- Penbutolol
- Perindopril Erbumine
- Pindolol
- Practolol
- Propranolol
- Quinapril
- Ramipril
- Sotalol
- Spirapril
- Telmisartan
- Timolol
- Trandolapril
- Valsartan
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