
bromfenac
Bromfenac is a prescription eye drop. It helps relieve eye pain and inflammation after adults get cataract surgery. It works as a nonsteroidal anti-inflammatory drug (NSAID). Bromfenac is available in a few strengths: 0.07% (brand name Prolensa and generic) and 0.09% (generic only). The usual dose is 1 drop in the affected eye once a day, starting the day before surgery and continuing for 2 weeks after surgery. Side effects can include eye pain and blurry vision.
What is Bromfenac?
What is Bromfenac used for?
- Eye pain and eye inflammation after cataract surgery in adults
How Bromfenac works
Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) that's used as an eye drop. It works by blocking a protein in your body that causes inflammation.
When you put bromfenac in your eye, it helps relieve eye pain, swelling, and inflammation. This is helpful for your eye to recover after cataract surgery.
Drug facts
| Common Brands | Prolensa |
|---|---|
| Drug Class | NSAID |
| Controlled Substance Classification | Not a controlled medication |
| Generic Status | Lower-cost generic available |
| Availability | Prescription only |
More on Bromfenac essentials
Side effects of Bromfenac
The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
- Blurry vision (up to 8%)
- Eye pain (up to 8%)
- Feeling like there's something in your eye (up to 8%)
- Sensitivity to light (up to 8%)
Less Common Side Effects
- Other eye irritation (e.g., burning, stinging, itching, redness)
Bromfenac serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Allergic reaction: hives; rash; blisters; swelling around the eye; swelling of the face, lips, or tongue; trouble breathing
More on Bromfenac side effects
The following Bromfenac side effects have also been reported
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
Blurred vision
change in color vision
decreased vision or other changes in vision
difficulty seeing at night
red, sore eyes
sensitivity to light
tearing
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Abnormal sensation in the eye
burning or stinging of the eye
feeling of having something in the eye
headache
itching of the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
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Pros and cons of Bromfenac
Pharmacist tips for Bromfenac
- Use bromfenac once a day. Start using the eye drops 1 day before your cataract surgery. Keep using the drops on the day of your surgery and also for the next 2 weeks. This helps lower eye pain and swelling from the procedure.
- Wash your hands before placing bromfenac drops in your eye. Also don't touch the dropper tip with your hands and don't let the tip touch your eye or any other surface. This helps prevent getting germs in your eye and eye infections.
- If you wear contact lenses, take them out before each time you use bromfenac. This medication has a preservative in it that can damage the contacts. Wait at least 10 minutes before you put your lenses back into your eye(s).
- How to use bromfenac: Tilt your head back and gently pull down your lower eyelid to make a small pocket. With the other hand, hold the eye drop bottle upside down right above your eye. Then, gently squeeze 1 drop into the pocket. Close your eye and press a finger on the inner corner of your eye near your nose for a minute. This keeps the medication in your eye instead of draining into your tear duct and nose.
- If you use other eye drops with bromfenac: Use each eye medication at least 5 minutes apart. This makes sure your eye absorbs each medication fully.
- How to store bromfenac eye drops: Keep the medication at room temperature between 59ºF and 77ºF.
- If you're pregnant: Talk to your eye specialist about the risks and benefits of using bromfenac. Eye drops are less likely to be absorbed into your body than medications taken by mouth. But NSAIDs, including bromfenac, are generally not recommended during pregnancy. This is because NSAIDs can harm your baby. Your eye specialist can decide if a different medication is a better choice, especially later in pregnancy.
Risks and warnings for Bromfenac
Bromfenac can cause some serious health issues. This risk may be even higher for certain groups. If this worries you, talk to your doctor or pharmacist about other options.
Allergic reaction
- Risk factors: Allergy to sulfites | Asthma | Sensitive to aspirin or other NSAIDs
Bromfenac 0.07% and 0.09% eye drops contain sulfite. This inactive ingredient can sometimes cause allergic reactions in certain people at risk. Tell your prescriber if you know you're allergic or sensitive to sulfites. Keep in mind that people with asthma might be more likely to be sensitive to sulfites.
Also let your prescriber know if you've ever had a reaction to aspirin or other NSAIDs. It's possible that you might have a similar reaction to bromfenac.
Stop using bromfenac and get medical help right away if you have an allergic reaction to the medication. Watch for rash, hives, swelling around the eye or face, or trouble breathing.
Slower healing
- Risk factors: Also using steroid eye drops
Bromfenac eye drops can slow how fast your eye heals after cataract surgery. Your eye might heal even more slowly if you also need to use steroid eye drops, like prednisolone (Pred Forte). Talk to your eye specialist if you're worried about how your eye is healing.
Bleeding in the eye
- Risk factors: History of bleeding problems | Taking other medications that raise your risk of bleeding
Bromfenac can raise your risk of bleeding in your eye after eye surgery. Tell your eye specialist if you have a bleeding problem. Also tell them if you take medications that can make you more likely to bleed, such as blood thinners. Call your eye specialist if you notice blood spots on your eye, especially if you've just had eye surgery.
Problems with the cornea
- Risk factors: History of problems with the cornea | Dry eye | Multiple eye surgeries | Complicated eye surgery | Rheumatoid arthritis | Diabetes | Using bromfenac for a long time
Bromfenac eye drops can cause problems with your cornea, the clear front part of your eye. They can include inflammation (called keratitis), corneal thinning, injury, or ulcers. In rare cases, these problems can affect your vision. Tell your eye specialist if you've had cornea problems or several eye surgeries in the past. They can help check your risk of these cornea problems.
Use bromfenac exactly as prescribed. Don't use it longer than prescribed before or after surgery. This helps lessen your risk of cornea problems. Call your optometrist or ophthalmologist right away if you notice changes in your vision, worse eye pain, or more eye irritation.
Remove contact lenses before using bromfenac
Bromfenac eye drops contain a preservative that can damage contact lenses. If you wear contact lenses, take them out each time before placing bromfenac drops in your eye. You'll need to wait at least 10 minutes before you put your contacts back in.
Bromfenac dosage
Interactions between Bromfenac and other drugs
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Abciximab
- Aceclofenac
- Acemetacin
- Acenocoumarol
- Amiloride
- Amineptine
- Amitriptyline
- Amitriptylinoxide
- Amoxapine
- Amtolmetin Guacil
- Anagrelide
- Apixaban
- Ardeparin
- Argatroban
- Aspirin
- Balsalazide
- Bemiparin
- Bendroflumethiazide
- Benzthiazide
- Betamethasone
- Betrixaban
- Bismuth Subsalicylate
- Bivalirudin
- Budesonide
- Bufexamac
- Bumetanide
- Cangrelor
- Celecoxib
- Certoparin
- Chlorothiazide
- Chlorthalidone
- Choline Magnesium Trisalicylate
- Choline Salicylate
- Cilostazol
- Citalopram
- Clomipramine
- Clonixin
- Clopamide
- Clopidogrel
- Cortisone
- Cyclopenthiazide
- Cyclosporine
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Deflazacort
- Desipramine
- Desirudin
- Desmopressin
- Desvenlafaxine
- Dexamethasone
- Dexibuprofen
- Dexketoprofen
- Diazoxide
- Dibenzepin
- Diflunisal
- Digoxin
- Dipyridamole
- Dipyrone
- Dothiepin
- Doxepin
- Droxicam
- Duloxetine
- Edoxaban
- Enoxaparin
- Eplerenone
- Epoprostenol
- Eptifibatide
- Escitalopram
- Ethacrynic Acid
- Etodolac
- Etofenamate
- Etoricoxib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Feverfew
- Floctafenine
- Flufenamic Acid
- Fluocortolone
- Fluoxetine
- Flurbiprofen
- Fluvoxamine
- Fondaparinux
- Furosemide
- Ginkgo
- Gossypol
- Heparin
- Hydrochlorothiazide
- Hydrocortisone
- Hydroflumethiazide
- Ibuprofen
- Iloprost
- Imipramine
- Indapamide
- Inotersen
- Ketoprofen
- Lepirudin
- Levomilnacipran
- Lithium
- Lofepramine
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Magnesium Salicylate
- Meadowsweet
- Meclofenamate
- Mefenamic Acid
- Melitracen
- Meloxicam
- Mesalamine
- Methotrexate
- Methyclothiazide
- Methylprednisolone
- Metolazone
- Milnacipran
- Morniflumate
- Nabumetone
- Nadroparin
- Naproxen
- Nefazodone
- Nepafenac
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nortriptyline
- Olsalazine
- Opipramol
- Oxaprozin
- Oxyphenbutazone
- Paramethasone
- Parecoxib
- Parnaparin
- Paroxetine
- Pemetrexed
- Pentosan Polysulfate Sodium
- Pentoxifylline
- Phenindione
- Phenprocoumon
- Phenylbutazone
- Phenyl Salicylate
- Piketoprofen
- Piroxicam
- Polythiazide
- Prasugrel
- Prednisolone
- Prednisone
- Proglumetacin
- Propyphenazone
- Proquazone
- Protein C
- Protriptyline
- Reboxetine
- Reviparin
- Rivaroxaban
- Rofecoxib
- Salicylamide
- Salicylic Acid
- Salsalate
- Sertraline
- Sibutramine
- Sodium Salicylate
- Spironolactone
- Sulfasalazine
- Sulindac
- Tacrolimus
- Tenofovir Disoproxil Fumarate
- Tenoxicam
- Tianeptine
- Tiaprofenic Acid
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Tolfenamic Acid
- Tolmetin
- Torsemide
- Trazodone
- Treprostinil
- Triamterene
- Trichlormethiazide
- Trimipramine
- Trolamine Salicylate
- Valdecoxib
- Venlafaxine
- Vilazodone
- Vorapaxar
- Vortioxetine
- Warfarin
- Xipamide
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Acebutolol
- Alacepril
- Anisindione
- Atenolol
- Azilsartan
- Azilsartan Medoxomil
- Benazepril
- Betaxolol
- Bisoprolol
- Candesartan Cilexetil
- Captopril
- Carteolol
- Carvedilol
- Celiprolol
- Dicumarol
- Enalapril
- Enalaprilat
- Eprosartan
- Esmolol
- Fosinopril
- Irbesartan
- Labetalol
- Levobunolol
- Lisinopril
- Losartan
- Metipranolol
- Metoprolol
- Moexipril
- Nadolol
- Nebivolol
- Olmesartan Medoxomil
- Oxprenolol
- Penbutolol
- Perindopril Erbumine
- Pindolol
- Practolol
- Propranolol
- Quinapril
- Ramipril
- Sotalol
- Spirapril
- Telmisartan
- Timolol
- Trandolapril
- Valsartan
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