Taltz Offers Another Monthly Psoriasis Treatment

Roni Shye
Roni Shye, PharmD BCGP BCACP, is a licensed pharmacist in the states of Florida, Ohio, and Pennsylvania.
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Newly approved injection Taltz (ixekizumab) will offer another treatment option for plaque psoriasis.

The American Academy of Dermatology estimates that nearly 7.5 million people in the United States suffer from psoriasis. It can cause itchy, dry, scaly patches of skin, and comes along with many complications and other diseases, including arthritis, depression, obesity, diabetes, and high blood pressure.

What is Taltz?
Taltz is a new monthly injection used to treat adults with moderate-to-severe plaque psoriasis.

Is there anything unique about Taltz, compared to other psoriasis meds?

No. Taltz is a once-monthly dosing option (after a few more frequent initial doses to get you started). Cosentyx (secukinumab), another monthly psoriasis medication, is in the same class of drugs as Taltz, and also treats moderate-to-severe plaque psoriasis.

Cosentyx is actually used for a few related conditions as well, include psoriatic arthritis—while Taltz is only approved to treat plaque psoriasis.

How does Taltz work?

The active ingredient in Taltz works deep inside of your cells, disrupting certain signals. This blocks a certain protein that causes inflammation.

How will Taltz be available?
Taltz will be available in an /mL dose, dispensed in an autoinjector or a pre-filled syringe.

How is Taltz used?

Once you’ve gone through the initial dosing steps, the recommended dose is a single injection every four weeks.

To start with though, you’ll use two injections at week 0 (your first dose), followed by a single injection at weeks 2, 4, 6, 8, 10, and 12.

What are the side effects of Taltz?

The most common side effects associated with Taltz are upper respiratory tract infections (common cold or sinus infections), injection site reactions, and fungal infections.

When will Taltz be available?
Taltz should be available soon—in the second quarter of 2016, according to its manufacturer, Lilly.

Other than Cosentyx, are there any other alternatives to Taltz?

Yes. There are several medications that are similar to Taltz, but that work slightly different to treat moderate-to-severe psoriasis:

You may be most familiar with Enbrel or Humira—they’ve been top-selling medications over the past several years.

Want more information on Taltz?

See the announcement from the FDA here.

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