Key takeaways:
The typical Relpax (eletriptan) dosage for migraines is 20 mg or 40 mg at the first sign of a migraine attack. If needed, you can take a second dose at least 2 hours later if your migraine hasn’t resolved or returns. The maximum amount you can take in 24 hours is 80 mg.
Relpax hasn’t been studied for treating more than 3 migraine attacks in a 30-day period. If you need to take it more often, talk to your healthcare professional about your options.
There are ways to save on Relpax, which is available as a brand-name medication and generic versions. GoodRx offers exclusive discounts on brand-name Relpax, regardless of your insurance status.
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If you experience migraine headaches, your healthcare team may prescribe a triptan medication such as Relpax (eletriptan) for fast relief. Relpax works by binding to receptors (binding sites) in the brain, which causes blood vessels to narrow and blocks pain signals.
Knowing the right Relpax dose and how to take it can help you get the best results while lowering the risk of side effects. Here’s what to know about typical Relpax dosages for adults, including how much to take and when.
What’s the typical Relpax dosage for adults?
The typical Relpax dosage for migraines in adults is 20 mg or 40 mg taken by mouth at the first sign of a migraine. You can take your dose with or without food.
If your migraine doesn’t go away, or if it improves and then comes back, you can take a second dose at least 2 hours after the first dose. The maximum dosage amount is 80 mg in 24 hours.
Relpax is used to treat migraines that have already started, not to prevent them. It also hasn’t been studied for treating more than 3 migraine attacks in a 30-day period. If you find yourself needing to take it more often, your healthcare team may recommend adding a preventive medication.
Good to know: If you don’t take Relpax at the start of a migraine, you can still take a dose later during the attack. But it may not work as well when taken later.
Are there any Relpax dosage adjustments for health conditions?
Relpax doesn’t have specific dosage adjustments for most health conditions, including kidney disease and mild to moderate liver disease. However, it isn’t recommended for people with severe liver disease because it hasn’t been studied in this group.
Your healthcare professional will consider your overall health history when determining whether Relpax is a safe option for you.
What should you do if you take too much Relpax?
Taking more than the recommended dose of Relpax can increase the risk of serious cardiovascular problems, including heart attack, heart rhythm changes, and dangerously high blood pressure. Serotonin syndrome (too much serotonin in the body) and other issues are also possible. Symptoms to watch for include:
Chest pain or tightness
Fast or irregular heartbeat
Jaw or neck pain
Shortness of breath
Dizziness
Nausea and vomiting
Sweating
Hallucinations
Fever
Confusion
Muscle stiffness or twitching
If you think you may have taken too much Relpax, contact your healthcare professional or call Poison Control at 1-800-222-1222 for guidance. Seek emergency care right away if you have symptoms such as chest pain, trouble breathing, or any other issue that feels severe.
How to save on Relpax
There are ways to save on Relpax, which is available as both a brand-name medication and lower-cost generics. GoodRx coupons and manufacturer copay savings cards can help you save on your prescription.
Save with GoodRx. GoodRx offers exclusive discounts on brand-name Relpax, regardless of insurance status. Pay as little as $144.90 for six 40 mg tablets with the coupon. Generic Relpax costs as little as $25.99 with GoodRx at certain pharmacies.
Save with a copay savings card. If you have commercial insurance that covers Relpax, you could pay as little as $4 per month with a copay savings card.
The bottom line
Relpax (eletriptan) is an oral triptan medication that’s used to treat migraines in adults. The typical Relpax dosage is 20 mg or 40 mg taken at the first sign of a migraine attack. If your migraine hasn’t resolved or improves but comes back, you can take a second dose at least 2 hours after the first dose. Don’t exceed 80 mg total in a 24-hour period. Relpax also hasn’t been studied for treating more than 3 migraine attacks in a 30-day period.
Taking too much Relpax can increase the risk of serious side effects, including cardiovascular problems and serotonin syndrome. To lower this risk, be sure to take Relpax exactly as prescribed. Ask your prescriber or pharmacist if you have questions about your Relpax dosage.
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References
Camber Pharmaceuticals. (2025). Eletriptan hydrobromide- eletriptan hydrobromide tablet, film coated [package insert]. DailyMed.
Norteman, K., et al. (2024). Eletriptan. StatPearls.
Poison Control. (n.d.). Get Poison Control help online now. National Capital Poison Center.




