What should I watch for?
Visit your doctor for checks on your progress. You will need to have regular blood tests while on this medicine. Report any new symptoms promptly.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body's ability to fight infections. Try to avoid being around people who are sick.
Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after the last dose.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
Side Effects to watch for
Side effects that you should report to your doctor or health care professional as soon as possible:
- allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
- breathing problems
- chest pain or tightness
- fever or chills, sore throat
- severe nausea, vomiting
- signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems
- signs and symptoms of high blood sugar such as dizziness; dry mouth; dry skin; fruity breath; nausea; stomach pain; increased hunger or thirst; increased urination
- signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
- stomach pain
- unusual bleeding or bruising
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
What may interact with this drug?
Do not take this medicine with any of the following medications:
- certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- certain medicines for seizures like carbamazepine, fosphenytoin, phenobarbital, phenytoin, primidone
- St. John's Wort, hypericum perforatum
This medicine may also interact with the following medications:
- antiviral medicines for HIV or AIDS
- certain antibiotics like clarithromycin, erythromycin, telithromycin
- certain medicines for blood pressure, heart disease, irregular heart beat
- certain medicines for depression, anxiety, or psychotic disturbances
- certain medicines for stomach problems like famotidine, dexlansoprazole, esomeprazole, lansoprazole, omeprazole, pantoprazole, rabeprazole
- certain medicines that treat or prevent blood clots like warfarin
- ergot alkaloids like dihydroergotamine, ergotamine
- grapefruit juice
- other medicines that prolong the QT interval (cause an abnormal heart rhythm)