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Levetiracetam (Spritam) is an expensive drug used with other medications to treat certain types of seizures. This drug is less popular than comparable drugs. There are currently no generic alternatives to Spritam. It is not covered by most Medicare and insurance plans, but manufacturer and pharmacy coupons can help offset the cost. Compare anti-epileptics.
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Spritam Side Effects

What should I watch for?

Visit your doctor or health care professional for a regular check on your progress. Wear a medical identification bracelet or chain to say you have epilepsy, and carry a card that lists all your medications.

It is important to take this medicine exactly as instructed by your health care professional. When first starting treatment, your dose may need to be adjusted. It may take weeks or months before your dose is stable. You should contact your doctor or health care professional if your seizures get worse or if you have any new types of seizures.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

The use of this medicine may increase the chance of suicidal thoughts or actions. Pay special attention to how you are responding while on this medicine. Any worsening of mood, or thoughts of suicide or dying should be reported to your health care professional right away.

Women who become pregnant while using this medicine may enroll in the North American Antiepileptic Drug Pregnancy Registry by calling 1-888-233-2334. This registry collects information about the safety of antiepileptic drug use during pregnancy.

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Common and Rare Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Aggressive or angry

anxiety

change in personality

chills

cough or hoarseness

crying

depersonalization

diarrhea

dry mouth

euphoria

fever

general feeling of discomfort or illness

headache

hyperventilation

irregular heartbeats

irritability

joint pain

loss of appetite

lower back or side pain

mental depression

muscle aches and pains

nausea

painful or difficult urination

paranoia

quick to react or overreact emotionally

rapidly changing moods

restlessness

shaking

shivering

shortness of breath

sleepiness or unusual drowsiness

sore throat

stuffy or runny nose

sweating

trouble sleeping

unusual tiredness or weakness

vomiting

Less common

Bloody nose

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

clumsiness or unsteadiness

discouragement

dizziness or lightheadedness

double vision

earache

feeling of constant movement of self or surroundings

feeling sad or empty

increase in body movements

loss of bladder control

loss of memory

mood or mental changes

outburst of anger

pain or tenderness around the eyes and cheekbones

problems with memory

redness or swelling in the ear

seizures

sensation of spinning

shakiness and unsteady walk

shakiness in the legs, arms, hands, or feet

tightness of the chest

tiredness

trembling or shaking of the hands or feet

trouble concentrating

unsteadiness, trembling, or other problems with muscle control or coordination

Incidence not known

Attempts at killing oneself

being forgetful

bleeding gums

blistering, peeling, or loosening of the skin

bloating

blood in the urine or stools

bloody, black, or tarry stools

blurred vision

changes in vision

chest pain

constipation

dark urine

difficulty with moving

fast heartbeat

fever with or without chills

general feeling of tiredness or weakness

high fever

increase in body movements

indigestion

itching

light-colored stools

muscle pains or stiffness

painful or difficult urination

pains in the stomach, side, or abdomen, possibly radiating to the back

pale skin

pinpoint red spots on the skin

red skin lesions, often with a purple center

red, irritated eyes

sores, ulcers, or white spots on the lips or in the mouth

stomach pain, continuing

swollen glands

swollen joints

thoughts or attempts at killing oneself

trouble with balance

twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs

uncontrolled jerking or twisting movements of the hands, arms, or legs

uncontrolled movements of the lips, tongue, or cheeks

unexplained bleeding or bruising

unusual bleeding or bruising

upper right abdominal or stomach pain

weight loss

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Loss of strength or energy

muscle pain or weakness

pain

tender, swollen glands in the neck

trouble swallowing

unusual weak feeling

voice changes

Less common

Body aches or pain

burning, dry, or itching eyes

change in the color of the skin

congestion

cough increased

rash

sneezing

Incidence not known

Hair loss or thinning of the hair

skin rash, encrusted, scaly, and oozing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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