The following side effects may get better over time as your body gets used to the medication. Let your healthcare provider know immediately if you continue to experience these symptoms or if they worsen over time.
Common Side Effects
Side effects from ertugliflozin:
- Genital fungal infection
- Urinary tract infection
- Headache
Side effects from metformin:
- Diarrhea
- Nausea
- Vomiting
- Passing gas
- Stomach discomfort
- Indigestion
- Weakness
- Headache
Less Common Side Effects
- Back pain
- Common cold symptoms
- Feeling thirsty
- More urination
- Vaginal itching
- Weight loss
Segluromet serious side effects
Contact your healthcare provider immediately if you experience any of the following.
- Buildup of lactic acid: confusion, feeling weak or tired, fast heartbeat, rapid breathing, no appetite, nausea, vomiting, feeling cold or clammy
- Serious genital infection: fever; pain, tenderness, redness, or swelling in the genital area
- Ketoacidosis (high ketone levels in the blood): shortness of breath, dry mouth, fruity-smelling breath, feeling very tired, vomiting, stomach pain
Source: DailyMed
The following Segluromet side effects have also been reported
Side effects that you should report to your care team as soon as possible:
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dehydration—increased thirst, dry mouth, feeling faint or lightheaded, headache, dark yellow or brown urine
- Diabetic ketoacidosis (DKA)—increased thirst or amount of urine, dry mouth, fatigue, fruity odor to breath, trouble breathing, stomach pain, nausea, vomiting
- Genital yeast infection—redness, swelling, pain, or itchiness, odor, thick or lumpy discharge
- High lactic acid level—muscle pain or cramps, stomach pain, trouble breathing, general discomfort and fatigue
- Infection or redness, swelling, tenderness, or pain in the genitals, or area from the genitals to the back of the rectum
- Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, trouble concentrating
- New pain or tenderness, change in skin color, sores or ulcers, infection of the leg or foot
- Urinary tract infection (UTI)—burning when passing urine, passing frequent small amounts of urine, bloody or cloudy urine, pain in the lower back or sides
Side effects that usually do not require medical attention (report these to your care team if they continue or are bothersome):
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